University of Colorado

Takasago International Corporation

Monell Chemical Senses Center

Sheseido Co., Ltd.

Diego Restrepo

Juliet T Gopinath

Emily A Gibson

Victor M Bright

Richard L Weir

Baris Ozbay

Andrew Sharp

Regan Andrew Zane

Kenneth A Gall

Zorana B Popovic

Gary K Beauchamp

Robert D Niederriter

Dudley Finch

Tsutomu Saito

Mark E Siemens

Brendan M Heffernan

Masahiro Tanida

Stephanie A Meyer

George Gomez

Shoji Nakamura

Shinichi Wachi

Yoshirou Okazaki

Yasuhiro Takashima

Zoya Popovic

The present disclosure relates optical imaging devices and methods useful in biological and medical imaging applications. In one embodiment, an optical imaging device includes a flexible lightguide having a first end and a second end, the output of the source of pulsed infrared radiation being optically coupled to the first end of the flexible lightguide; a lens assembly attached to and optically coupled to the second end of the flexible lightguide, the lens assembly comprising a variable-focus lens element, the a variable-focus lens element having a tunable focal length; and a photodetector coupled to the flexible lightguide to detect radiation propagating from the second end toward the first end of the flexible lightguide. The optical imaging devices and methods can be used in both confocal and multi-photon techniques.

Optical imaging devices and variable-focus lens elements, and methods for using them

Sub-diffraction limited fluorescent images using a fiber-based stimulated emission depletion (STED) microscope are reported. Both excitation and depletion beams are transported through polarization-maintaining fiber and a lateral resolution of 100 nm has been achieved.

Methods and systems for stimulated emission depletion microscopy

Exemplary systems and methods are provided for collecting/harvesting direct current (DC) power received from a power source(s). The system comprises a controlled impedance power controller comprises a power converter configured to present a positive equivalent resistive load to the at least one power source over a range of input power levels. Exemplary systems and methods are provided for collecting radio frequency (RF) power. An exemplary system comprises at least two rectenna elements, a power controller, and a DC combining circuit. The DC combining circuit is associated with the at least two rectenna elements and the DC combining circuit is configured to dynamically combine the at least two rectenna elements in one of a plurality of series/parallel configurations. The power controller is configured to control the DC combining circuit to achieve a desired overall power output from the at least two rectenna elements.

Systems and methods for receiving and managing power in wireless devices

There is provided a slowly implantable electrode. A coating for an electrode, the coating includes a shape-memory polymer. A method for inserting an electrode into brain tissue by inserting an implantable electrode having a shape-memory polymer coated electrode into brain tissue.

Shape-memory polymer coated electrodes

Adjuvants for preventing adaptation to odors comprising one or compounds having the following formula (1): ##STR1## wherein R1 is a C1 to C8 lower alkyl group or a C7 to C9 aralkyl group, and R2 is a hydrogen atom or a C1 to C8 lower alkyl group, are described, as are compositions containing the same, and methods for preventing the adaptation to odors. Methods for increasing intracellular calcium ion levels and for prolonging the sensory response of chemoreceptive cells also described.

Adjuvants and methods for raising intracellular calcium ion concentration

Growing community of inventors

Littleton, CO, United States of America

Diego Restrepo