Nlt Spine Ltd.

Seaspine, Inc.

Arbel Medical Ltd.

Blue Tree Technologies Ltd.

Other

Icecure Medical Ltd.

Aleph Farms Ltd.

Didier Toubia

Oded Loebl

Tzony Siegal

Dvir Keren

Netanel Sharabani

Alexander Levin

Haim Yustein

Asher Vitner

Zach Barnea

Revital Mali

Miron Kaganovich

Yinnon Elisha

Neta Lavon

Anna Bodanovsky

Lilach Eyal-Waldman

An adjustable implant includes a telescopic body with first and second portions in sliding engagement, and a deflectable linkage formed from a first linking segment, an intermediate segment and a second linking segment pivotally interconnected so that adjustment of a length of the telescopic body causes a corresponding deflection of the deflectable linkage. The first linking segment and the second linking segment are formed with projecting features that provide a partial gear engagement between the first and second linking segments such that, during adjustment of a length of the telescopic body and corresponding deflection of the deflectable linkage, pivotal motion of the first and second linking segments relative to the intermediate segment about the first and second pivot axes occurs in a fixed ratio defined by the partial gear engagement.

Adjustable implant

The present invention relates to compositions and methods for mass production of pluripotent stem cells derived from non-human-animal, particularly in a form of aggregates suitable for a variety of uses, particularly to mass production of aggregates of bovine-derived pluripotent stem cells for use in cell grown meat cultures and in production of cell based meat products.

Pluripotent cell aggregates and use thereof

A laterally deflectable asymmetric implant for implanting into a body may comprise a deflectable piece having distal and proximal ends and assuming a straightened insertion state. The backbone may abut or interconnect with said deflectable piece at the distal end of the deflectable piece. In a fully deflected state the implant may define an asymmetric shape, e.g. a D-shaped loop, defining an at least partially enclosed volume. The deflectable piece may comprise a sequence of segments interconnected at effective hinges. Longitudinal pressure applied to the proximal end of the deflectable piece (or applied to the backbone in an opposite direction) may cause relative longitudinal movement between the backbone and the proximal end of the deflectable piece and may generate outward horizontal movement of the deflectable piece away from the backbone. In one embodiment, the implant is implanted using lateral access into an anterior zone of a vertebra and deployed posteriorly.

Laterally deflectable implant

Methods and systems are disclosed for selectively removing naturally-occurring sugars in beverages in an effective, affordable and scalable manner.

Methods and systems for producing low sugar beverages

Method and systems are disclosed for selectively removing naturally-occurring sugars in beverages in an effective, affordable and scalable manner.

An expanding implant () includes a base () having a contact surface () for contacting a first region of tissue and a displaceable portion. () having a contact surface () for contacting a second region of tissue. The base () has a proximal portion () in sliding engagement with, a distal portion () so as to define an arcuate path of relative motion between the proximal and distal portions. The base assumes an initial state with a first arcuate extent and is adjustable towards a second State by changing an: extent of overlap between the proximal and distal portions to vary an. arcuate extent of the base. First and second rigid linking segments () are in articulating connection with the distal and proximal portions of the base, and with the displaceable portion such that adjustment of the base from the initial state towards the second state causes an increase in a distance between the contact surfaces of the base and the displaceable portion.

Adjustable arcuate implant

An implant having a base with a first contact surface and a hinged element, hingedly interconnected with a first portion of the base, providing a second contact surface. The first portion of the base is displaceable relative to a second portion so that the base can be shortened from an initial length towards a second length. A linking segment is hingedly connected to both the second portion of the base and to the hinged element so that shortening of the base causes the linking segment to push a region of the hinged element away from the base, thereby changing an angle of the second contact surface relative to the first contact surface.

Orthopedic implant with adjustable angle between tissue contact surfaces

An adjustable implant () has a base () and a displaceable element () providing opposing tissue contact surfaces (). A linkage () is pivotally connected to the displaceable element. A linkage mover (), engaged so as to be displaceable along the base, is associated with the linkage () so as to define a displaceable pivot location () for pivotal motion of the linkage relative to the base, in certain preferred embodiments, the base () has an internally threaded track () in which a threaded segment of the linkage mover () is engaged, so that rotation of the threaded segment about its central axis advances the linkage mover along the threaded track, thereby displacing the displaceable pivot locations and adjusting a separation between the first contact surface and at least part of the second contact surface.

An intervertebral implant has at least one arm () pivotally connected to a base (). At least one worm gear configuration includes a worm in () mounted within the base () so as to be rotatable, and a set of gear teeth () associated with the arm (). When the worm () is rotated about its central axis, the arm () is driven through a range of pivotal motion relative to the base so as to change an angle of inclination between a direction of elongation () of the arm and the direction of elongation () of the base. Embodiments of the invention include devices with a hollow proximal worm allowing access into the implant via the worm, distally deployed worms, and devices with a pair of worm gear assemblies that operate synchronously or independently.

Worm-gear actuated orthopedic implants and methods

A medical device () includes an implant body () with a number of segments () hingedly interconnected so as to assume a straightened state for delivery and a flexed or roughly curved deployed state. Implant body may have engagement elements on at least two different segments, for example on a majority of segments. An elongated locking element anchored at the distal segment of the implant body may have projections for at least each engagement element. Tension applied to the locking element biases the implant body from the straightened state to the flexed deployed state. When the locking element is deflected to reach the curved deployed state, flexing segments of the implant body lock by matching engagement elements of the implant body with projections of the locking element. A very secure lock may be formed to prevent opening after deployment.

Medical device lock mechanism

Deflectable implants, systems and methods for implanting deflectable implants are disclosed. The deflectable implant includes at least one sequence of segments, the sequence includes at least two segments, the segments being interconnected at effective hinges, the sequence assuming a straightened or low curvature insertion state for insertion into the body, the sequence being deflectable to a fully deflected state defined by abutment of abutment features of adjacent of the segments. The deflectable implant includes further a linkage mechanically linked to at least part of at least one of the sequences of segments for deflecting the at least one sequence of segments from the insertion state towards the fully deflected state wherein the at least one sequence is at least part of a loop structure assuming a low profile folded state with the at least one sequence in the insertion state, and wherein deflection of the at least one sequence towards the fully deflected state generates an open state of the loop structure and wherein the loop defines an enclosed volume.

Growing community of inventors

Raanana, Israel

Didier Toubia