Centre National De La Recherche Scientifique

Ipsen Pharma S.a.s.

Societe De Conseils De Recherches Et D'applications Scientifiques (s.c.r.a.s.)

Other

Arkema France

Université Paul Sabatier (toulouse Iii)

Sanofi

Societe De Conseils De Recherches Et D'applications Scientifiques

Isochem

Centre De La Recherche Scientifique (cnrs)

Centre National De La Recherche Scientifique-cnrs

Ipsen Pharma

Universite Paul Sabatier Toulouse

Didier Bourissou

Blanca Martin-Vaca

Jean-Bernard Cazaux

Roland Cherif-Cheikh

Guy Bertrand

Heinz Gornitzka

Anca Dumitrescu

Olivier Thillaye Du Boullay

Christophe Navarro

Frederic Lacombe

Frédéric Lacombe

Bianca Martin-Vaca

Frédéric Ben

Magalie Graullier

Anne-Paula De Sousa Delgado

Eric Didier

Stéphanie Magnet

Martin Montes

Harivardhan Reddy Lakkireddy

Aurelie Alba

Didier Bazile

Martin-Vaca Blanca

Fethi Bensaid

Stephanie Greco

Serge Sable

Michel Veillard

Laurence Lachamp

Stéphanie Gazeau-Bureau

Abderrhamane Amgoune

Hanh Nguyen Ngoc

Damien Delcroix

Anne De Sousa Delgado

Lidija Vranicar

Emmanuel Marchal

Roland Chérif-cheikh

Roland Cherif-cheikh

Aurélie Alba

Frederic Ben

Stéphanie Greco

The present invention relates to a method for preparing a copolymer from at least one cyclic monomer selected from: a lactone, a lactam, a carbonate, a lactide and a glycolide, an oxazoline, an epoxide, a cyclosiloxane, comprising the step consisting of reacting said cyclic monomer in the presence of a substituted phosphorus-containing compound. It also relates to the polymer composition obtained according to this method, as well as the uses thereof, notably as antistatic additives, biocompatible materials, as membranes for treatment of effluents or in electrochemical systems for energy storage.

Method for preparing a polymer from at least one cyclic monomer

The present invention relates to a parenteral, sustained and controlled release, semisolid formulation comprising an end-capped oligomer and at least one active substance without any supplementary viscosity reducing agent or excipient.

Sustained release formulations comprising very low molecular weight polymers

The present invention relates to novel conjugates of active principles grafted to a polymer, to the nanoparticles comprising them, to their preparation and to their polymeric intermediates.

Polymeric conjugates of active principles, their process of preparation and their polymeric intermediates

The present invention relates to a process for the preparation of a lactone or lactam homopolymer, comprising the stage consisting in reacting a lactone or lactam with a nonpolymeric initiator comprising at least one hydroxyl or thiol functional group in a nonchlorinated solvent in the presence of a sulfonic acid of formula R&#x2014;SOH. It also relates to the polymer composition thus obtained and to its uses, in particular as antistatic additive.

Process for the preparation of polylactones and polylactams

The present invention relates to the use of a system composed of a base and of a sulphonamide, as a catalyst for the ring-opening (co)polymerization of lactones. The present invention also relates to novel sulphonamides and to a process for the ring-opening (co)polymerization of lactones comprising the use of sulphonamides in combination with a base as a catalytic system.

Catalytic systems for the ring-opening (co)polymerization of lactones

The use of a catalytic ring-opening lactide and glycolide (co)oligomerization system consisting of a strongly acidic ion-exchange resin-type polymeric catalyst and a (co)oligomerization additive, and a lactide and glycolide (co)oligomerization method using said catalytic system, are disclosed.

Use of a catalytic system for lactide and glycolide (co) oligomerization

A catalytic lactide and glycolide copolymerization system comprising a trifluoromethane sulfonate as a catalyst and copolymerization additive and a copolymerization process.

Catalytic lactide and glycolide (co)polymerization system

The invention concerns a method for preparing poly(-hydroxy acids), the polymerization reaction being performed in controlled manner in the presence of a catalytic system including a base, said base being a 5- or 6-membered aromatic heterocycle comprising at least one endocyclic nitrogen atom, provided that when the base is used alone in the catalytic system, it does not represent pyridine, 2-methylpyridine, 2,6-dimethylpyridine or 2-methoxypyridine. The invention also concerns poly(-hydroxy acids) of formula (IV). Finally, the invention concerns the use of a poly(-hydroxy acid), obtainable by the inventive method, for vectoring active principles or for making biomaterials.

Method for controlled polymerization of o-carboxy anhydrides derived from &#x3b1;-hydroxy acids

The invention relates to a novel method for the synthesis of 2,5-dioxane-1,4-diones having formula (I), comprising the oxidation of the ketone function of a cyclic compound having formula (II), wherein R, R, Rand Rindependently represent the hydrogen atom, halo, (C-C) alkenyl, (C-C)cycloalkyl, cyclohexenyl and a radical having formula &#x2014;(CH)&#x2014;V&#x2014;W. 

Method for synthesis of 2,5-dioxane-1,4-diones

The invention concerns the use of zinc derivatives of general formula (I) wherein: Lrepresents a group of formula: &#x2014;E(R)(R')(R&#x2033;), &#x2014;E(R) (R&#x2032;) or &#x2014;E(R); E is an atom of group 15; Land Lindependently represent a group of formula: &#x2014;E(R)(R&#x2032;)(R&#x2033;), &#x2014;E(R)(R&#x2032;) or &#x2014;E(R), or together form a chain of formula &#x2014;L&#x2032;&#x2014;A&#x2014;L&#x2032;&#x2014;; A represents a saturated or unsaturated chain comprising one, two or three elements of group 14; L&#x2032;and L&#x2032;independently represent a group of formula &#x2014;E(R)(R&#x2032;) &#x2014;E(R) or &#x2014;E&#x2014;; Eis an element of group 14; Eis an element of group 15; Eis an element of group 16; R, R&#x2032;, R&#x2033;, R, R&#x2032;and Rrepresent various groups, as (co) polymerisation catalysts of cyclic esters 

Use of zinc derivatives as cyclic ester polymerization catalysts

A subject of the present invention is new compounds having a lanthanide and having a tridentate ligand, a process for their preparation and their use in particular as polymerization catalysts.

Polymerization catalysts

The use of stannylenes and germylenes of general formula (I) wherein: M represents a tin or geranium atom; Land Lindependently represent a group of formula: -E(R) (R') (R&#x2033;), -E(R) (R&#x2032;) or -E(R)) or together form a chain of formula -L&#x2032;-A- L&#x2032;; A represents a saturated or unsaturated chain comprising one, two or three elements of group 14; L&#x2032;and L&#x2032;, represent, independently, a group of formula: -E(R) (R&#x2032;)-, E(R)- or -E-; Eis an element of group 14; Eis an element of group 15; Eis an element of group 16; R, R&#x2032;, R&#x2033;, R, R&#x2032;and Rrepresent variable groups as polymerization catalysts of heterocycles.

Use of stannylenes and germylenes as polymerization catalysts for heterocycles

The invention relates to new compounds having an element of group 12 and having a tridentate ligand, a process for their preparation and their use in particular as a polymerization catalyst.

Polymerisation catalysts

Polymerisation catalyst

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Plaisance du Touch, France

Didier Bourissou