Warsaw Orthopedic, Inc.

Medtronic, Inc.

Didier Billy

Jeffrey L Scifert

Scott Mitchell Vickers

Mirian Gillissen

William F McKay

Kathy L Remsen

Lilian Kornet

Rogier Receveur

Nicolaas M Lokhoff

Karel F A A Smits

Tim Dirk Jan Jongen

Jean Joseph Gerardus Rutten

Sylvia Weijzen-Engels

Karel FAA Smits

Methods for making an osteoimplant are provided. In one embodiment the method includes applying a mechanical force to an aqueous slurry of insoluble collagen fibers to entangle the insoluble collagen fibers so as to form a semi-solid mass of entangled insoluble collagen fibers; and lyophilizing the semi-solid mass of entangled collagen fibers to form the osteoimplant. An osteoimplant containing entangled insoluble collagen fibers is also provided.

Osteoimplant comprising an insoluble fibrous polymer

Described are implantable, malleable medical materials comprising mineral particles, insoluble collagen fibers, and a gel-forming polysaccharide component and/or another added gel-former. The malleable medical materials can be used treat bone or other tissue defects in patients, including in conjunction with biologically active factors such as osteogenic proteins. Also described are methods and materials that can be used to prepare the malleable medical materials.

Malleable multi-component implants and materials therefor

A lead including one or more electrodes having circuitry associated therewith. Each such electrode includes a circuit extending along and conforming to at least a portion of an inner surface of the electrode. The circuit includes an isolation substrate contacting at least a portion of the inner surface of the cylindrical electrode portion, a first contact electrically isolated from the electrode portion by the isolation substrate and an integrated circuit electrically coupled to the first contact and the electrode.

Lead apparatus

Growing community of inventors

Maastricht, Netherlands

Didier Billy