Sarepta Therapeutics, Inc.

Other

Diane Elizabeth Frank

Richard Keith Bestwick

Bao Zhong Cai

Baozhong Cai

Mitchell Martini

Katie Thomas

Ross Shimabuku

Alan I Frank

Cindy B Schiavon

Fred Joseph Schnell

Antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon 44 skipping are described.

Exon skipping compositions for treating muscular dystrophy

Provided herein are processes for preparing an oligomer (e.g., a morpholino oligomer). The synthetic processes described herein may be advantageous to scaling up oligomer synthesis while maintaining overall yield and purity of a synthesized oligomer.

Processes for preparing oligomers

Provided herein are processes for preparing an oligomer (e.g., a morpholino oligomer). The synthetic processes described herein may be advantageous to scaling up oligomersynthesis while maintaining overall yield and purity of a synthesized oligomer.

A completely automatic, player operable, currency accepting instant lottery machine including a random number generator containing air-mixed balls which are marked on their surfaces with commonly recognized digits and also marked with a uniform pattern of bar code markings arranged in tall and narrow strips. After a mixing process, the balls which have randomly settled into the lower settlement pockets of the transparent random number generator are caused to rotate by jets of compressed air directed tangentially at their surfaces in opposite directions. Bar code scanning light pens located adjacent the settlement pockets and in close proximity to the rotating, randomly selected balls read the bar codes and transmit electronic signals to a computer in the machine which compares the randomly generated number to the player's previously selected number to determine if a successful match has occurred, in which case, a redeemable ticket is dispensed.

Growing community of inventors

Cambridge, MA, United States of America

Diane Elizabeth Frank