Obsidian Therapeutics, Inc.

Dexue Sun

Vipin Suri

Dan Jun Li

Brian Dolinski

Byron Delabarre

Grace Y Olinger

Mara Christine Inniss

Michael N Gladstone

Celeste Richardson

Scott Francis Heller

Abhishek Kulkarni

James A Storer

Dhruv Kam Sethi

Vijaya Balakrishnan

Michelle Lynn Ols

Jennifer Leah Gori

Peter L Barrett

Kutlu Goksu Elpek

Molly Reed Perkins

Michelle Fleury

Shyamsundar Subramanian

Colleen Foley

Jeremy Hatem Tchaicha

Tariq A Kassum

Meghan C Langley

Benjamin J Primack

Tucker Read Ezell

Geetha Hanna Mylvaganam

James Storer

The present disclosure provides regulatable biocircuit systems. Such systems provide modular and tunable protein expression systems in support of the discovery and development of therapeutic modalities.

Membrane bound IL12 compositions and methods for tunable regulation

The present invention is related to compositions and methods for the regulated and controlled expression of proteins.

DHFR tunable protein regulation

The present invention relates to compositions and methods for the regulated and controlled expression of proteins. Methods for inducing anti-cancer immune responses in a subject are also provided.

PDE5 compositions and methods for immunotherapy

The present invention provides regulatable biocircuit systems. Such systems provide modular and tunable protein expression systems in support of the discovery and development of therapeutic modalities.

Regulated biocircuit systems

The present disclosure provides drug responsive domains derived from human carbonic anhydrase 2 that can modulate protein stability for human interleukin 15 (IL15) payloads, as well as compositions and methods of use thereof.

CA2 compositions and methods for tunable regulation

Growing community of inventors

Cambridge, MA, United States of America

Dexue Sun