Gilead Sciences, Inc.

Lilac Therapeutics, Inc.

Devleena M Shivakumar

Hyung-Jung Pyun

Lan Jiang

Hong Yang

Hongyan Guo

Jiayao Li

Qiaoyin Wu

Ana Zurisadai Gonzalez Buenrostro

Hang Chu

Xiaochun Han

Gregg M Schwarzwalder

Michael L Mitchell

Jennifer R Zhang

Scott D Schroeder

Nathan D Shapiro

Manoj C Desai

Lianhong Xu

John Edward Knox, Jr

Anna E Hurtley

Matthew J Von Bargen

Zachary E R Newby

Amy S Lee

Gregg M Schwarzwälder

Ana Z Gonzalez Buenrostro

Compounds for use in treating or preventing human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R, R, L, W, W, X, Y, and Z are as defined herein. Methods associated with the preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Bridged tricyclic carbamoylpyridone compounds and their pharmaceutical use

The present disclosure relates generally to modulators of human glycolate oxidase enzyme and methods of use and manufacture thereof.

Heterocyclic carboxylate compounds as glycolate oxidase inhibitors

The present disclosure relates generally to compounds, of Formula I Also disclosed are pharmaceutical compositions comprising said compounds and methods of making said compounds. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.

Bridged tricyclic carbamoylpyridone compounds and uses thereof

The present disclosure relates generally to compounds, of Formula I: Also disclosed are pharmaceutical compositions comprising said compounds and methods of making said compounds. The compounds of the disclosure are useful in treating or preventing human immunodeficiency virus (HIV) infection.

Growing community of inventors

Menlo Park, CA, United States of America

Devleena M Shivakumar