Lifescan Corporation

Devin McAllister

Lorin Philip Olson

Koon-Wah Leong

Maria Teodorczyk

Ernest J Kiser

Vadim V Yuzhakov

Borzu Sohrab

A system employing an integrated analyte test strip including a biosensor and lancet is disclosed. The integration of lancet and the sensor elements eliminates the need to align the sensor to the biologic fluid sample after a lancet and lancing device are used in combination to pierce the skin. The system preferably includes a device comprising two body portions that slide relative to each other to both cock and fire a test strip at a target site. Meter reading and test strip disposal may be accomplished by removing the device from the target site. The device preferably employs a magazine loaded with test strips, with one strip being taken from the magazine each time the device is actuated. It preferably also includes a magazine in a cap to store spent test strips for disposal. The device may be turned on an off simply by removal and return of the cap.

Minimal procedure analyte test system

Methods and devices for electrochemically detecting a change in the viscosity of a fluid are provided. In the subject methods, a fluid sample (e.g., a whole blood sample) is introduced into an electrochemical test strip's electrochemical cell using a micro-needle integrated into one of oppositely spaced apart working and reference electrodes. An electric potential is applied to the electrochemical cell to first achieve a steady state cell current. A decrease in the steady state cell current is then detected and related to a change in viscosity of the sample. In many embodiments, the sample is blood and the change in viscosity is related to the onset of coagulation in the blood sample, and often the PT of the blood sample. An electrochemical test strip includes an electrochemical cell and an integrated micro-needle. The electrochemical cell includes oppositely spaced apart working and reference electrodes and a reagent mixture (e.g., a redox couple and a coagulation catalyzing agent). The micro-needle is integrated into one of the working and reference electrodes of the electrochemical cell.

Electrochemical test strip with an integrated micro-needle and associated methods

Methods of fabricating devices for collecting a sample of physiological and for measuring a characteristic, e.g., an analyte concentration, of the sampled physiological sample. The devices are in the form of a test strip which include a biosensor and at least one skin-piercing element which is a planar extension of a portion of the biosensor. The fabrication methods provide various or forming the test strip and the skin-piercing element.

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San Jose, CA, United States of America

Devin McAllister