Indiana University

Deven L Shinholt

Martin F Jarrold

Andrew W Alexander

Staci N Anthony

A quadrupole mass filter and method for operating the filter are described. Sample ions, each having a mass-to-charge ratio, are passed to a quadrupole at least one AC voltage is applied thereto to separate the ions by incrementally varying a frequency of the at least one AC voltage within a first range of frequencies and, for each of at least some of the incremental frequencies in the first range of frequencies, incrementally varying an amplitude of the at least one AC voltage within a range of amplitudes, wherein each incremental frequency and incremental amplitude pair of the at least one AC voltage creates a different band pass filter in the quadrupole through which produced ions having a different corresponding mass-to-charge ratio pass to a detector.

Frequency and amplitude scanned quadrupole mass filter and methods

A quadrupole mass filter and method for operating the filter are described. AC voltages are applied to the quadrupole to separate ions based on mass-to-charge ratio. Frequency is scanned with a simultaneous amplitude scan. Ions are measured over a broad m/z range with high resolution. A resolving power of about 1,200 was demonstrated. Ions were observed for m/z values over 150,000 Th.

Growing community of inventors

Pflugerville, TX, United States of America

Deven L Shinholt