Rush University Medical Center

Deva Chan

Vincent Wang

John D Sandy

Anna H K Plaas

Jun Li

Anna HK Plaas

Anna Hk Plaas

One aspect of the invention provides methods for classifying the quality of a repair response after injury to a joint of a subject. In one embodiment, the method includes providing a tissue sample from the injured region of the joint and determining expression levels in the sample of a plurality of genes, including at least those genes listed in Table 1, Table 2 and Table 3. Another aspect of the invention provides methods of treating a human or veterinary subject having an injury to a joint based on the classification of the quality of the repair response.

Transcriptomic index for characterizing the cellular repair response after soft tissue injury in diarthrodial joints

One aspect of the Invention provides methods for classifying the quality of a repair response after injury to a joint of a subject. In one embodiment, the method includes providing a tissue sample from the injured region of the joint and determining expression levels in the sample of a plurality of genes, including at least those genes listed in Table 1, Table 2 and Table 3, Another aspect of the Invention provides methods of treating a human or veterinary subject having an injury to a joint based on the classification of the quality of the repair response.

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Chicago, IL, United States of America

Deva Chan