R.p.scherer Technologies, Inc.

Alk-abello A/s

Desmond Yik Teng Wong

Henrik Hugo Jacobi

Susan Gerrard Banbury

Michael Hall

Christian Gauguin Houghton

Stig Aasmul-Olsen

Lisa Garrett

Annette Roemmelmayer Lundegaard

Lise Lund Maerkedahl

Jan Sondergaard Andersen

Kerry Mallindine

Owen James Murray

Leon Grother

Andrzej Jan Brzozowski

The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided.

Allergen dosage form

The invention disclosed herein relates to a pharmaceutical composition comprising a carrier and an active ingredient, wherein the carrier is at least one fish gelatin predetermined on the basis of the molecular weight profile of the gelatin. In some embodiments, particularly when the concentration of carrier comprises a relatively lower percentage of the total composition, the carrier may be exclusively a high molecular weight fish gelatin, or may be comprised of a mixture with standard molecular weight gelatin in which high molecular weight gelatin comprises a predominant portion. In those embodiments where the concentration of carrier comprises a relatively larger percentage of the total composition, the carrier may be an exclusively standard molecular weight fish gelatin, or may be comprised of a mixture in which standard molecular weight gelatin comprises a predominant portion. Thus, compositions may be designed to optimize performance for various required gelatin concentration formulations.

Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight

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Swindon, United Kingdom

Desmond Yik Teng Wong