Harvard College

Des White

Donald Elliot Ingber

David J Mooney

Michael Super

Edward J Doherty

Mark J Cartwright

Omar Abdel-Rahman Ali

Alexander G Stafford

Amanda Graveline

Benjamin Seiler

The present invention provides vaccine compositions and methods of producing such compositions. Other embodiments of the invention include methods of treating a pathogen infection, methods of vaccinating a subject against a pathogen infection, and methods for treating an antibiotic-resistance bacterial infection in a subject in need thereof. In further embodiments, the invention includes methods of decreasing the level of a pathogen in a subject having a pathogen infection, methods of increasing the surviving rate of a subject having a pathogen infection, methods of reducing the level of pain associated with a pathogen infection, and methods of reducing the level of distress associated with a pathogen infection in a subject in need thereof. Novel scaffold compositions and opsonin-bound or lectin-bound pathogen compositions, and uses thereof, are also provided herein.

Pathogen vaccines and methods of producing and using the same

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Boston, MA, United States of America

Des White