Other

Prodigene, Inc.

Derrick Witcher

John A Howard

Elizabeth E Hood

James C Register, Iii

Terry EuClaire Meyer

Chris L Baszczynski

David J Peterson

Wesley B Bruce

David A Peterson

A Gururaj Rao

Thomas H Czapla

Sheila E Maddock

A method for commercial production of aprotinin entails heterologous expression of the protein in plants, preferably at a level such that aprotinin accounts for at least 0.1% of the total extracted protein. An aprotinin-expressing plant also has potential of increased insecticidal resistance by virtue of producing the protein. A genetic map of the integration locus allows identification of plants derived from the transgenic plant. This approach also reveals genetic loci on a plant chromosome that support high levels of gene expression and can be used as site of integration for expression of other genes of interest.

Commercial production of aprotinin in plants

A method for commercial production of GUS entails heterologous expression of the protein in plants, in native conformation, at an expression level such that avidin represents at least 0.1% of total extracted protein. A genetic map of the integration locus allows for the identification of the GUS-expressing plant. Genetic loci on a plant chromosome are revealed that support high levels of GUS expression and that can be used as a site of integration for high level expression of other genes of interest.

Commercial production of .beta.-glucuronidase in plants

A method for commercial production of avidin entails heterologous expression of the protein in plants, in native conformation, at an expression level such that avidin represents at least 0.1% of total extracted protein. A genetic map of the integration locus allows for the identification of the avidin-expressing plant. Genetic loci on a plant chromosome are revealed that support high levels of avidin expression and that can be used as a site of integration for high level expression of other genes of interest.

Commercial production of avidin in plants

Growing community of inventors

Urbandale, IA, United States of America

Derrick Witcher