Pacesetter, Inc.

Derrick W Reed

Paul A Levine

Yougandh Chitre

Heidi Hellman

Eliot L Ostrow

Rohan More

Systems and methods are provided for use by implantable medical devices equipped to deliver multi-site left ventricular (MSLV) pacing. Sequential MSLV is associated with a relatively long post-ventricular atrial blanking (PVAB) period that might limit the detection of pathologic rapid organized atrial tachycardias (OAT). In one example, sequential MSLV cardiac resynchronization therapy (CRT) pacing is delivered within a tracking mode. A possible atrial tachycardia is detected based on the atrial rate exceeding an atrial tachycardia assessment rate (ATAR) threshold. The device then switches to either single-site LV pacing or simultaneous MSLV pacing, thereby effectively shortening the PVAB to detect additional atrial events that might otherwise be obscured, and thereby permitting the device to more reliably distinguish OATs (such as atrial flutter) from sinus tachycardia. The device may also employ an automatic mode switch (AMS) threshold set higher than the ATAR threshold for use in switching from tracking modes to nontracking modes.

Systems and methods for use by an implantable medical device for controlling multi-site CRT pacing in the presence of atrial tachycardia

Conditions resulting from acute decompensation such as pulmonary edema may be indicated based on analysis of respiration signals. In some embodiments a respiration signal is derived from an intracardiac electrogram ('IEGM') signal. In some embodiments one or more non-rate-based parameters are derived from a detected respiration signal to identify a pulmonary edema condition. In some embodiments a warning may be generated or therapy administered to a patient in response to an indication of pulmonary edema.

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Calabasas, CA, United States of America

Derrick W Reed