Optos Plc

Derek Swan

Gonzalo Muyo

Dan Gray

Stephen Pemberton

Martin Thomson

William J Brown

Jano Van Hemert

Alistair Gorman

Daniel Gray

Robert Wall

Michael E Sullivan

Anthony Corcoran

William Brown

A computer-implemented method of searching for a region indicative of a pathology in an image of a portion of an eye acquired by an ocular imaging system, the method comprising: receiving image data defining the image; searching for the region in the image by processing the received image data using a learning algorithm; and in case a region in the image that is indicative of the pathology is found: determining a location of the region in the image; generating an instruction for an eye measurement apparatus to perform a measurement on the portion of the eye to generate measurement data, using a reference point based on the determined location for setting a location of the measurement on the portion of the eye; and receiving the measurement data from the eye measurement apparatus.

Detection of pathologies in ocular images

A method of determining control parameters of a retinal treatment system comprising acquiring an image of a retina of a subject's eye using an imaging laser and an optical system of the retinal treatment system, presenting an image of the retina to a user of the retinal treatment system, receiving from the user location data of the retinal image that locates at least one treatment site of the retina, receiving from the user a required laser light pattern for use on the treatment site, using the location data to determine a location control parameter which causes the optical system to direct laser light from a treatment laser of the retinal treatment system to the treatment site, and using the required laser light pattern to determine a pattern control parameter which causes the treatment laser to produce a laser light pattern which passes through the optical system and results in the required laser light pattern at the treatment site.

Retinal treatment

An ophthalmoscope () and method for scanning a fundus () of an eye (), comprising a light system () which produces linear light, a scanner () which receives at least some of the linear light and is movable about a scan axis to produce a 1D scan of the at least some linear light, and a scan transfer system () which receives the 1D scan from the scanner and transfers the 1D scan to the eye, wherein the scanner is positioned in the ophthalmoscope such that it receives the at least some of the linear light substantially along the scan axis, the scan transfer system positioned in the ophthalmoscope such that a pupil of the eye is provided at a focal point of the system, and the scanner is positioned in the ophthalmoscope and the scan transfer system is configured to transfer the 1D scan from the scanner through the focal point at the eye pupil and onto the eye fundus.

Ophthalmoscopes

An ophthalmoscope () comprising a light source (), a first scanner (), a first scan transfer element (), a second scanner (), and a second scan transfer element (), which provide a two-dimensional scan of incident light from an apparent point source at a pupillary point of an eye () onto the fundus of the eye, and which descan a two-dimensional scan of return light from the fundus of the eye to provide return light from an apparent point source at the first scanner, wherein the first scan transfer element comprises a free-form element which has a shape defined to provide aberration correction of the return light from the fundus of the eye.

A scanning laser ophthalmoscope for scanning the retina of an eye is provided comprising a light source emitting a beam of light, scan relay elements, wherein the light source and the scan relay elements provide a two-dimensional scan of the light beam which is transferred from an apparent point source at a pupillary point of the eye to the retina of the eye, and a static aberration correction element which has a shape defined to provide correction of aberrations of at least some of the scan relay elements and a location within the ophthalmoscope chosen to provide correction of aberrations of at least some of the scan relay elements, which location maintains transfer of the beam of light from the apparent point source at the pupillary point of the eye to the retina of the eye.

A scanning laser ophthalmoscope (SLO) for imaging the retina of an eye comprises a source () of collimated light, a scanning device (), a scan transfer device () and a detector (). The scan transfer device has a first focus () at which an apparent point source is provided and a second focus () at which an eye () may be accommodated. The scan transfer device transfers a two-dimensional collimated light scan from the apparent point source into the eye. An optical coherence tomography (OCT) system () is combined with the SLO, the OCT system providing OCT reference and sample beams. The OCT sample beam () propagates along the same optical path as of the SLO collimated light through the scan transfer device. An aberration compensator () automatically compensates for systematic aberrations and/or changes in wavefront introduced by scanning elements and the scan transfer device as a function of scan angle.

Ophthalmoscope

The invention provides an apparatus and method for scanning, imaging and treating the retina of an eye. The apparatus () comprises a source of collimated light (), a two-dimensional scanning device () having two axes of rotation (), wherein the axes of rotation () are orthogonal and substantially planar, and wherein the source of collimated light () and the two-dimensional scanning device () combine to provide a two-dimensional collimated light scan from a point source (). The apparatus () further comprises a scan transfer device (), wherein the scan transfer device () has two foci () and the point source () is provided at a first focus point () of the scan transfer device () and an eye () is accommodated at a second focus point () of the scan transfer device (), and wherein the scan transfer device () transfers the two-dimensional collimated light scan from the point source () into the eye ().

Retinal imaging apparatus and method

The invention provides an apparatus and method for illuminating, imaging and treating the retina of an eye. The apparatus () comprises at least one light source (), wherein the at least one light source () is adapted to provide collimated light () from a plurality of point sources (), and wherein each point source () lies on an arc (), and wherein the at least one light source () is configured to direct collimated light () from each point source () along the radius () of the arc () towards a center point () of the arc (), and wherein, in use, the apparatus () is arranged such that the center point () of the arc () is substantially coincident with the pupillary point () of the eye (), such that collimated light () is transmitted from the point source () through the pupillary point () of the eye () to illuminate the retina ().

The present invention provides a scanning ophthalmoscope for scanning the retina of an eye and a method of scanning the retina of an eye. The ophthalmoscope () comprises a source of collimated light (), a first scanning element (), a second scanning element () and a scan relay device () having two foci (). The source of collimated light (), the first and second scanning elements () and the scan relay device () combine to provide a two-dimensional collimated light scan () from an apparent point source (). The scanning ophthalmoscope () further comprises a scan transfer device (), wherein the scan transfer device () has two foci () and at least one vertex () and the apparent point source () is provided at a first focus () of the scan transfer device () and an eye () is accommodated at a second focus () of the scan transfer device (), and wherein the scan transfer device () transfers the two-dimensional collimated light scan () from the apparent point source () into the eye (). The two foci () of the scan relay device () and the two foci () of the scan transfer device () define a first plane and the two foci () and the at least one vertex () of the scan transfer device () define a second plane and wherein the first and second planes are substantially parallel.

Scanning ophthalmoscopes

This disclosure is directed to systems and methods for determining a correction for distortion in eye representations of an ophthalmoscope. A digital model of an optical system including the ophthalmoscope and a model eye may be constructed. The digital model may be transmitted to a ray tracing system. A ray may be passed through the optical system onto a surface of the model eye. A measurement of the ray at the surface of the model eye, with distortion, may be calculated and an angular position of a horizontal scanning element and an angular position of a vertical scanning element can be determined. Using the horizontal scanning angle and vertical scanning angle, a measurement of the ray at the surface of the model eye, without distortion, may be calculated and compared to the measurement with distortion to determine a correction for distortion in eye representations of the ophthalmoscope.

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Dunfermline, United Kingdom

Derek Swan