Ultima Genomics, Inc.

New Matter, Inc.

Derek Schulte

Steven Menchen

Gilad Almogy

Nathan Beckett

Avishai Bartov

Kristopher Barbee

Jamie Michael Sullivan

Mark Pratt

Denis Pristinski

Dumitru Brinza

Abizar Lakdawalla

Steven Schell

Norvan Gorgi

Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate configured to rotate. The open substrate can comprise an array of immobilized analytes. A solution comprising a plurality of probes may be directed, via centrifugal force, across the array during rotation of the substrate, to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via continuous rotational area scanning of the substrate.

Methods and systems for analyte detection and analysis

Provided are methods for biological sample processing and analysis. A method can comprise providing a substrate configured to rotate. The substrate can comprise an array having immobilized thereto a biological analyte. A solution comprising a plurality of probes may be directed, via centrifugal force, across the substrate during rotation of the substrate, to couple at least one of the plurality of probes with the biological analyte. A detector can be configured to detect a signal from the at least one probe coupled to the biological analyte, thereby analyzing the biological analyte.

Methods for biological sample processing and analysis

Provided are systems for biological sample processing and analysis. A system can comprise a substrate configured to rotate. The substrate can comprise an array configured to immobilize a biological analyte. A fluid flow unit comprising a fluid channel can be configured to dispense a solution comprising a plurality of probes. The solution may be directed, via centrifugal force, across the substrate during rotation of the substrate, to couple at least one of the plurality of probes with the biological analyte. A detector in optical communication with the array can be configured to detect one or more signals from the at least one probe coupled to the biological analyte.

Systems for biological sample processing and analysis

A system and method for calibrating the gap between a 3D printer extruder nozzle and build platform are disclosed. To calibrate, the build platform is moved laterally in the horizontal plane and the extruder nozzle is moved downward toward the build platform. While moving the nozzle downward, the velocity of the build platform or the power required to move the build platform in the horizontal plane is monitored. A drop in velocity or an increase is power required to move the build platform is detected when the extruder nozzle contacts the build platform due to kinetic friction. The vertical height of the extruder nozzle is then set or calibrated relative to the build platform based on the position of the extruder nozzle when the contact was detected.

Calibration system and method for determination of relative position of two components in multi-axis motion system

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Los Angeles, CA, United States of America

Derek Schulte