Genentech, Inc.

F. Hoffmann-la Roche Ag

Denny Christensen

Ulla Grauschopf

Mayumi Naito Bowen

Markus Hemminger

Flora Felsovalyi

Robert Müller

Frank Bamberg

A method of preparing a prefilled syringe is disclosed that includes obtaining a syringe barrel and a needle adaptor cap assembled on the tip of the syringe barrel, wherein the needle adaptor cap has a rubber element tightly sealing the orifice of the tip of the syringe barrel and the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel is sterilized by a first sterilizing. Filling a drug substance into an interior of the syringe barrel and sealing the interior of the syringe barrel. Packaging the syringe barrel with a rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. Providing a second external surface sterilizing of the packaged syringe barrel with the rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel.

Prefilled syringe and method of preparing a prefilled syringe

Growing community of inventors

South San Francisco, CA, United States of America

Denny Christensen