Acclarent, Inc.

The General Hospital Corporation

Children's Medical Center Corporation

Dennis S Poe

Ketan P Muni

Andy T Nguyen

Hung V Ha

Randy S Chan

Sivette Lam

Marc Dean

Holger Sudhoff

Jetmir Palushi

Henry F Salazar

Jeffrey B Everett

Heather M Wozniak

Mahboob U Rahman

Hyon K Choi

A dilation catheter includes a shaft and an expandable element. The shaft includes a proximal portion and a distal portion. The distal portion includes a tip and a bend. The tip is sized and configured to pass through an isthmus of a Eustachian tube (ET). The bend is proximal to the tip. The bend is formed at an angle configured to provide insertion of the tip into the isthmus of the ET via an ear canal associated with the ET. The expandable element is disposed at the distal portion of the shaft. The expandable element is configured to transition between a non-expanded state and an expanded state. The expandable element in the non-expanded state is configured for insertion into the ET via the isthmus. The expandable element in the expanded state is configured to dilate the ET.

System and method for treatment of eustachian tube from middle ear approach

A plug is configured to maintain position within a Eustachian tube of a patient. The plug includes a proximal portion and a distal portion. The proximal portion includes a first body dimensioned bear radially outwardly against the Eustachian tube of the patient. The distal portion includes an anchoring assembly that is configured to lock the plug in the Eustachian tube of the patient. The plug may be formed of a bioabsorbable material.

Plug with isthmus anchor for treating patulous Eustachian tube

Disclosed herein are methods for treating immune-mediated ear disorders, such as IMCVDs, or their symptoms, involving administration of a therapeutically-effective amount of a TNF antagonist, such as etanercept or infliximab, or a therapeutically-effective amount of a pyrimidine synthesis inhibitor, such as leflunomide.

Treatments for immune-mediated ear disorders

Growing community of inventors

Chestnut Hill, MA, United States of America

Dennis S Poe