Eli Lilly and Company

Dennis P Smith

Hansen M Hsiung

Xing-Yue Zhang

The instant invention provides the porcine pVIP receptor protein. The invention also provides DNA compounds encoding the pVIP receptor, recombinant DNA cloning and expression vectors comprising that DNA, and recombinant host cells comprising those vectors. The invention also provides methods of making the pVIP receptor in recombinant and solid phase systems. The invention also provides methods of using the pVIP receptor in assay systems. The invention also provides methods of using the disclosed DNA sequences as probes to isolate and characterize pVIP receptors and corresponding DNA sequences from other species.

Porcine vasoactive intestinal peptide receptor and DNA

The present invention comprises novel expression control sequences that promote transcription of DNA. The novel sequences have been positioned for expression of structural genes encoding bovine growth hormone derivatives on recombinant DNA expression vectors. The novel expression control sequences function in both Gram-positive and Gram-negative organisms and can be constructed by either DNA synthesizing instruments or by conventional modified phosphotriester methodology.

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Indianapolis, IN, United States of America

Dennis P Smith