Symbiontics, Inc.

E.i. Dupont De Nemours and Company

Harvard College

Dennis E Vaccaro

Stephen M Beverley

Frederico J Gueiros-Filho

Marcia J Stone

Paul J Durda

David J Green

Disclosed herein are novel medical devices, particular well-suited for sustained delivery of therapeutically-significant substances. Also disclosed are methods of making and using these delivery devices. Using these devices and methods, the present invention teaches sustained, targeted and reversible delivery of immunostimulating agents, as well as therapeutic agents such as enzymes, hormones and neurotransmitters, to name but a few.

Sustained delivery device and methods of making and using the same

Disclosed herein are novel medical devices, particular well-suited for sustained delivery of therapeutically-significant substances. Also disclosed are methods of making and using these delivery devices. Using these devices and methods the present invention teaches sustained, targeted and reversible delivery of immunostimulating agents, as well as therapeutic agents such as enzymes, hormones and neurotransmitters, to name but a few.

Sustained delivery device comprising a Leishmania protozoa and methods

A monoclonal hybridoma antibody with specificity for an antigen that is present on tumors of epithelial origin; the cell line secreting said antibodies; a process for selecting the cell line; a diagnostic process for detecting the antigen and a therapeutic process for neutrailization of the angtigen.

Monoclonal hybridoma antibody specific for a human epithelial antigen

Growing community of inventors

Wellesley, MA, United States of America

Dennis E Vaccaro