Ethicon, Gmbh

Depuy Mitek, Inc.

Mitek Surgical Products Inc.

Other

Johnson & Johnson Consumer Inc.

Depuy Synthes Products, Inc.

Codman & Shurtleff, Inc.

Brian H. Luscombe

Izi Bruker

Jack S. Pedlick

Daniel C. Rosenman

Dennis D. Jamiolkowski

Raymond Thal

Robert C. Di Luccio

Ilya Koyfman

Dennis D Jamiolkowski

Rao S Bezwada

Shalaby Wahba Shalaby

Sasa Andjelic

Shawn Thayer Huxel

Arindam Datta

Brian M Kelly

Yufu Li

Modesto Erneta

Hugh D Newman, Jr

Ilya S Koyfman

Jack S Pedlick

Frederick E Shelton, IV

Kevin L Cooper

Brian H Luscombe

Jason L Harris

Michael J Vendely

Iksoo Chun

Mora Carolynne Melican

Leo B Kriksunov

Anna Gosiewska

Ying Sun

Jeffrey M Wu

Daniel C Rosenman

J Jenny Yuan

Jerome R Morgan

Charles J Scheib

Mark S Zeiner

Bret William Smith

Omar J Vakharia

David W Overaker

Richard C Smith

Leslie Hamilton

Angelo G Scopelianos

Julia Hwang

Robert Nering

Alastair W Hunter

Gaoyuan Gavin Chen

Robert DiLuccio

Robert F Bencini

Francois Binette

Jackie J Donners

Mark D Timmer

Jesse G Nawrocki

Guanghui Zhang

Susanne Landgrebe

Anthony S Miksza

Christopher DeFelice

Robert C Di Luccio

Terry E Lawler

Daniel Steiger

Thu Anh Le

John DiGiovanni

Mark J Suseck

An-Min Jason Sung

Kelly R Brown

Jianguo Jack Zhou

Kevor S TenHuisen

Mark D Kenyon

Steven F Harwin

Donald F Koelmel

Kenneth Michael Keilman

Marc Wisnudel

Mark T Gaterud

Emil Richard Skula

Donald W Regula

Stephen J Rothenburger

Mark G Steckel

Donald G Hill

John Di Giovanni

Suzanne E Thompson

Henry Pokropinski, Jr

William J Zwaskis

Nicholas M Popadiuk

David Wasserman

Michael F Bregen

Keith A Seritella

Margaret M D'Aversa

Laurel L Rogers

John J Karl

Howard L Scalzo, Jr

Sung S Yi

Carl R Smith

Scott Evans Fitzgerald

Karl W Brennan

William Zwaskis

E Richard Skula

Sasa Andjeli&cacute;

Susan Cooper

Stuart L Cooper

Anh Le

Mark Cofone

Andrea Slater-Tomko

Mariann Sayer

Joseph R Thomas

Daniel J Spangler

Christopher Defelice

Hugh D Newman

Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.

Readily absorbable copolymer compositions for high strength sutures having enhanced strength retention post-implantation

A staple cartridge assembly comprising an implantable adjunct or layer assembly is disclosed. The implantable adjunct comprises a plurality of layers, wherein at least one of the layers has been melted to bond with one or more of the other layers of the implantable adjunct.

Implantable adjunct comprising bonded layers

The present invention relates devices capable of continuous and simultaneous expression of components of a multi-part biomedical composition with variable mixing ratios. The device has at least two syringes that contain the inter-reactive components of the multi-part biomedical composition. At least the barrel of the first syringe has a first retention compartment having a cross-sectional area dimension that is larger than the cross-sectional area of a second retention compartment. The first piston has a cross-sectional dimension that matches the inside cross-sectional dimension of the small dimensioned retention compartment, while a ring-shaped gasket is located within the large dimensioned retention compartment and has an outside cross-sectional dimension that matches an interior dimension of the large dimension retention compartment.

Methods and devices for forming biomedical coatings using variable mixing rations of multi-part compositions

Novel absorbable polymer blends are disclosed. The blends are useful for manufacturing medical devices having engineered degradation and breaking strength retention in vivo. The blends consist of a first absorbable polymeric component and a second absorbable polymeric component. The weight average molecular weight of the first polymeric component is higher than the weight average molecular weight of the second polymeric component. At least at least one of said components is at least partially end-capped by a carboxylic acid group. Further aspects are medical devices made therefrom.

Mechanically strong absorbable polymeric blend compositions of precisely controllable absorption rates, processing methods, and products therefrom

A novel high tensile strength semi-absorbable composite suture with minimized non-absorbable mass. The suture has a core made from a bioabsorbable polymer. The core is covered by a braided sheath. The braided sheath is made from an absorbable yarn and a bioabsorbable yarn. The bioabsorbable yarn is made from a least one filament of a bioabsorbable polymer. The nonabsorbable yarn is made from at least one filament of ultra high molecular weight polyethylene.

High strength suture with absorbable core and suture anchor combination

Devices and methods for placing an adjunct at a tissue treatment site prior to delivering staples through the tissue and adjunct are provided. In one embodiment, a flowable adjunct precursor can be deposited on the surface of the tissue at the tissue treatment site. The flowable adjunct precursor can be configured to solidify after deposition to form an adjunct. In another embodiment, an adjunct delivery device can include a non-stapling end effector configured to deliver an adjunct to a tissue treatment site. In either case, staples can be delivered through the adjunct and tissue after placement of the adjunct at the tissue treatment site.

Methods and devices for delivering and securing adjunct materials to a treatment site

Exoskeletal devices or sleeves that can be used with the delivery tube of an applicator device to help dispense fluids, typically flowable biocompatible materials such as hemostatic agents, adhesives, or sealants, onto specific sites in the human body for a medical reason are disclosed. The exoskeletal devices or sleeves are rigid, pre-shaped, and snappably or slidably affixed to the delivery tube. The exoskeletal devices or sleeves do not come into contact with the flowable biocompatible fluid being dispensed, and they can be placed at any position along the delivery tube to address different application situations. Once the exoskeletal device or sleeve is in place, it can optionally be locked onto the delivery tube to prevent further sliding under stresses when pushed against tissue. Multiple exoskeletal devices or sleeves can also be used to achieve more complicated shapes for hard-to-reach anatomical sites.

Rigid reinforcing exoskeletal sleeve for delivery of flowable biocompatible materials

Absorbable medical devices based on novel foams and films made from semi-crystalline, segmented copolymers of lactide and epsilon-caprolactone exhibiting long term absorption characteristics are disclosed. Also disclosed are methods of producing said foams and films, and useful polymer solutions.

Absorbable medical devices based on novel films and foams made from semi-crystalline, segmented copolymers of lactide and epsilon-caprolactone exhibiting long term absorption characteristics

Methods and devices for forming biomedical coatings using variable mixing ratios of multi-part compositions

Novel absorbable polymeric blends are disclosed. The blends have a first absorbable polymer type that is a polylactide polymer or a copolymer of lactide and glycolide and a second absorbable polymer type that is poly(p-dioxanone), wherein the first absorbable polymer type or the second absorbable polymer type or the first absorbable polymer type and the second absorbable polymer type additionally comprise a first polymeric component and a second polymeric component. The first polymeric component has a higher weight average molecular weight than the second polymeric component and at least one of said components is at least partially end-capped by a carboxylic acid. The novel polymeric blends are useful for manufacturing medical devices having dimensional stability, having engineered degradation and breaking strength retention in vivo. Also disclosed are novel absorbable medical devices made from these novel polymer blends, as well as novel methods of manufacture.

Absorbable polymeric blend compositions with precisely controllable absorption rates, processing methods, and dimensionally stable medical devices therefrom

A composition comprising: a benefit agent; at least one polymer including a polycaprolactone polymer; at least one lower alcohol; and at least one co-solvent; and a method for enhancing topical delivery of a benefit agent is disclosed.

Topical gel compositions including polycaprolactone polymer and methods for enhancing the topical application of a benefit agent

Adjunct materials and methods of using adjunct material to reinforce a staple line are provided. In general, an adjunct material can be used to maintain a seal in tissue and can prevent stapled tissue from tearing. In some embodiments, a surgical stapler can include a jaw having an adjunct material associated with the jaw. The adjunct material can be attached to tissue via staples deployed by the stapler. In some embodiments, an adjunct material can be a woven material having a single layer or multiple layers, and each layer can have different mechanical properties. In other embodiments, an adjunct material can have a single layer or multiple layers of nonwoven material, such as suture compressed into a three dimensional structure.

Woven and fibrous materials for reinforcing a staple line

Adjunct material and methods of using adjunct material to reinforce tissue in proximity to a staple line are provided herein. In general, the adjunct material can be used to maintain a seal in tissue, such as lung tissue, and prevent stapled tissue from tearing. This adjunct material can be coupled to a jaw of a surgical stapler, and can be deployed into tissue along with the staples. In some embodiments, the adjunct material can comprise an outer material encompassing an inner, hydrophilic swellable material. The outer material can be selectively dissolvable and/or absorbable. When the outer material is punctured by staples or otherwise penetrated, moisture is passed to the inner material which then swells and expands to transition to a predetermined shape to seal the tissue and prevent leaks from forming in the tissue. Portions of the inner material around the staple line can transition to a large radius.

Methods and devices for reinforcing a staple line

Growing community of inventors

Long Valley, NJ, United States of America

Dennis D Jamiolkowski