Lunaphore Technologies Sa

Deniz Eroglu

Diego Gabriel Dupouy

Pierre Joris

Marco Ammann

Ata Tuna Ciftlik

Giulia Cappi

Marta Comino

Benjamin Pelz

Biological sample processing system comprising an imaging unit () comprising a digital image processing system and at least one microscope including at least one lens (), a sample processing station () comprising a handling platform () including a support () and a displacement mechanism for moving the support (), and a sample processing unit () mounted on the handling platform (). The sample processing unit () comprises a tissue slide holder () for mounting thereon a tissue slide () with a biological sample () fixed thereon and a microfluidic cartridge holder () for mounting a microfluidic cartridge () thereon. The tissue slide holder () is coupled to the microfluidic cartridge holder () via a coupling () allowing the microfluidic cartridge and the tissue support to be mounted and removed from the sample processing unit in an opened position, and in a closed position for the tissue support () to be in sealing contact with the microfluidic cartridge (). The sample processing station comprises a plurality of said sample processing units mounted on the handling platform () and moveable from a position allowing mounting of the tissue slide, respectively microfluidic cartridge, or removal thereof, to a position in which the viewing window in the microfluidic cartridge holder () is positioned in alignment with the lens of said at least one microscope.

Biological sample processing system and microfluidic cartridge therefor

Microfluidic cartridge () comprising a sampling device () having a sealing ring () arranged to form a microfluidic chamber () when a support containing a biological sample is brought into contact with the sealing ring, and a microfluidic network device () configured to supply reagents to the microfluidic chamber. The sampling device further comprises inlet and outlet distribution networks () in fluid communication with the microfluidic chamber and a slide holder () to guide and position said support containing a biological sample on the sampling device. The microfluidic network device comprises a plurality of reagent inlet channels () fluidly connectable to reagent sources, at least one reagent outlet channel () fluidly connected to the sampling device inlet distribution network (), and a plurality of valves () operable to selectively connect the inlet channels to the at least one outlet channel. The sampling device () and microfluidic network device () are formed on a common microfluidic support () as a single part.

Microfluidic cartridge with built-in sampling device

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Lausanne, Switzerland

Deniz Eroglu