Steris Inc.

Denise K Pretzer

Nancy E Kaiser

Kevin A Tibbs

An antimicrobial lotion for topical use comprises an oil-in-water emulsion with a dispersant of emollient droplets in an oil phase and an antimicrobial agent in a water phase. The emollients moisturize the skin. Antimicrobial agents have a more rapid antimicrobial effect in an aqueous solution than in the oil phase. A combination of anionic and nonanionic surfactants stabilize the emulsion and maintain a cationic antimicrobial agent primarily in the water phase. The resulting lotion is gentle on the skin while providing more rapid antimicrobial effect than conventional lotions. With longer lasting antimicrobial agents, such as chlorhexidene, the lotion is rubbed into the skin and left on to continue moisturizing and killing microbes for up to 12 hours.

Fast-acting antimicrobial lotion with enhanced efficacy

A disinfectant hand wash includes Triclosan and a reduced amount of surfactants in order to reduce skin irritation while maintaining improved activity against Gram negative and Gram positive organisms, including Serratia marcescens. The hand wash includes an effective amount of Triclosan, preferably 0.2-3.0% and a non-aqueous solvent. Hexylene glycol, or a mixture of hexylene glycol and isopropanol as the non-aqueous solvent provide improved efficacy in killing skin-born microbes. The hand wash further includes less than about 10% surfactant, preferably less than 5%. The hand wash further includes a chelating agent, a thickener, a buffering agent, and water.

Triclosan skin wash with enhanced efficacy

A disinfectant hand wash includes triclosan and a reduced amount of surfactants in order to reduce skin irritation while maintaining improved activity against Gram negative and Gram positive organisms, including Serratia marcescens. The hand wash includes an effective amount of triclosan, preferrably 0.2-3.0% and a non-aqueous solvent. A mixture of hexylene glycol and isopropanol provide improved efficacy in killing skin-born microbes. The hand wash further includes 2-20% surfactant, preferrably at less than 10%. The hand wash further includes a chelating agent, a thickener, a buffering agent, and water.

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Chesterfield, MO, United States of America

Denise K Pretzer