Other

Bristol-myers Squibb Compnay

Denise Christine Grunenfelder

Richard Eric Olson

Upender Velaparthi

Jayakumar Sankara Warrier

Prasada Rao Jalagam

Saumya Roy

Robert G Gentles

Min Ding

Scott W Martin

Louis Stanley Chupak

Bireshwar Dasgupta

Chetan Padmakar Darne

Hasibur Rahaman

Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CRor N; Y is CRor N; R, R, R, R, R, R, R, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGKα) and diacylglycerol kinase zeta (DGKζ), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.

Substituted bicyclic compounds useful as T cell activators

Disclosed are compounds of Formula (I): or a salt thereof, wherein: R, R, R, R, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK&#x3b1;) and diacylglycerol kinase zeta (DGK&#x3b6;), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.

Substituted pyridopyrimidinonyl compounds useful as T cell activators

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Boston, MA, United States of America

Denise Christine Grunenfelder