Technicon Instruments Corporation

Miles, Inc., Successor in Interest To Technicon Instruments Corp.

Deng R Hwang

Mary E Scott

Eddie Hedaya

Bernard Loev

Michael J Malin

Phospholipid conjugate compounds derived from cardiac glycosides and sters useful in liposome immunoassays are disclosed as well as their method of preparation.

Phospholipid conjugates and their preparation

A substrate for .beta.-galactosidase having the general formula ##STR1## wherein X is halogen; Y is halogen, lower alkyl or hydrogen; W is lower alkyl or hydrogen; and Z is nitro.

Substrates for .beta.-galactosidase

Phospholipid conjugate compounds derived from cardiac glycosides and steroids useful in liposome immunoassays are disclosed as well as their method of preparation.

New phthalocyanin derivatives which can be used to differentiate basophils from other blood cells are disclosed. The compounds to which the present invention are quaternary salts of a substituted phthalocyanin structure wherein the substitutions are each independently hydrogen, sulfonate, or a C.sub.1 -C.sub.7 hydrocarbon, optionally containing at least one heteroatom, with the proviso that at least one of them is ##STR1## in which R.sub.1 -R.sub.3 are each independently lower alkyls, cycloalkyls or olefins of which at least one is C.sub.2 -C.sub.4 and two may join to form a ring; R.sub.4 is hydrogen or a C.sub.1 -C.sub.3 alkyl; n is an integer from 1 to 6; M is a polyvalent metal ion. It is preferred that at least two and especially at least three substitutions have the structure so set forth.

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Tarrytown, NY, United States of America

Deng R Hwang