Wisconsin Alumni Research Foundation

Immuron Limited

Dena Lyras

Eric Arthur Johnson

Marite Bradshaw

Julian Rood

Lucy Li

Glen Carter

Julian I Rood

Melanie Hutton

Bliss Cunningham

The present invention relates to methods and compositions for the treatment and/or prophylaxis ofassociated disease (CD AD). In particular, the invention relates to antibodies that bind toantigens and are capable of inhibitinginfection, at least one symptom ofassociated disease, shedding of, andassociated mortality. The compositions of the present application comprise: mammalian or avian antibodies which bind to aToxin B; and mammalian or avian antibodies that bind to avegetative cell antigen and/or aendospore antigen.

[object Object]

A system is used to express clostridial gene constructions in a clostridial host. A mobilizable transfer plasmid is described which permits the direct transfer of the plasmid, and genes carried on it, from E. coli into Clostridium species. A promoter is described for use in clostridial species. Also, a useful host strain is used which is nontoxigenic and which permits high levels of expression of clostridial genes using the clostridial promoter.

Expression system for clostridium species

Growing community of inventors

Heidelberg Heights, Australia

Dena Lyras