Southern Illinois University

Deliang Cao

This invention provides antibodies immunologically specific for human ARL-1 (also referred to AKR1B10), a species of the aldo-keto reductase superfamily of proteins. The invention also provides methods of making and methods of using said antibodies.

ARL-1 specific antibodies and uses thereof

Provided herein are methods and materials for diagnosing a bowel disease in a subject by detecting the presence or absence of a bowel disease marker. A bowel disease marker has been identified as AKR1B10 and may be useful in identifying subjects at risk for bowel disease, predicting bowel disease progression, and assessing a subject's response to therapy.

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Chatham, IL, United States of America

Deliang Cao