Celgene Corporation

Receptos, Inc.

Deepak Dalvie

Matthew David Alexander

Dehua Huang

Joshua Hansen

John J Sapienza

Matthew Daniel Correa

Lida R Tehrani

Veronique Plantevin-Krenitsky

Stephen Norris

Brandon Wade Whitefield

Virginia Heather Sharron Grant

Evan J Horn

Christopher Mayne

Roy L Harris, Iii

Kristen R Taylor Meadows

Veronique Plantevin-krenitsky

Brett Skolnick

Iii Roy L Harris

Provided herein are piperidine dione compounds having the following structure: wherein R, R, R, R, L, V, X, a and m are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.

Cereblon binding compounds, compositions thereof, and methods of treatment therewith

Provided herein are piperidine dione compounds having the following structure:

Methods of treating conditions for which S1P-mediated neuroprotection is medically indicated, comprising administering to a subject in need thereof an agonist of the sphingosine 1-phosphate receptor (S1P receptor); such as a compound having the following structure (See Formula 1): or a pharmaceutically acceptable salt, stereoisomer, homolog, hydrate or solvate thereof. 

Sphingosine 1 phosphate receptor agonists for neuroprotection

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Carlsbad, CA, United States of America

Deepak Dalvie