Neuravi Limited

Declan Lee

Aidan Duffy

Gillian Gunning

Diarmaid O'Keeffe

AnnaLisa Smullin

Thomas O'Malley

Maeve Holian

Thomas O'malley

A clot retrieval device is disclosed to remove clot from a blood vessel. The device can include a collapsed configuration and an expanded configuration. The device can include an inner expandable body with a framework of struts. The device can include an outer expandable body with a framework of struts that at least partially radially surrounding the inner expandable body. A distal portion of the outer expandable body can extend in the deployed configuration towards the outer expandable body to a greater extent than the inner expandable body, closed cells of the distal portion distally tapering and being smaller than cells proximal thereof in the outer expandable body. The plurality of closed cells of the distal portion can include a pair of axially aligned smaller diamond shaped cells formed by struts of the distal portion and positioned along upper and lower regions of the distal portion.

Clot retrieval device for removing clot from a blood vessel

A design capable of both mechanical thrombectomy and stenting for treating occlusions in the cerebral vasculature provides for a three-catheter setup. The first outer catheter has the largest diameter and can serve as a guide catheter while also being a sheath for the other catheters. The second deployment catheter can be configured for the aspiration of occlusions and can include a stepped or recessed section proximal of the distal tip that can act as a housing for a braided expandable stent. The outer diameter of this stepped section can be lined with an inflation device on top of which the braided stent sits. Internal to the second deployment catheter is a microcatheter which can deliver mechanical thrombectomy devices to the target site to retrieve an occlusion in the vessel, after which the stent can be expanded and implanted in the vessel.

Thrombectomy and stenting system

An improved insertion apparatus simplifies loading of neurovascular device into microcatheter. In one example, the insertion apparatus can include a tapered distal tip, allowing the insertion apparatus to reach the microcatheter with no gap. In another example, the insertion apparatus can include an uneven outer surface along its longitudinal body through laser ablation of material to form protrusions, forming taper features, forming wave patterns or thread extrusions.

Neurovascular insertion tool

Designs are disclosed for devices capable of removing both firm and soft clots from body vessels that can have dual layers where an inner expandable body of cells runs within an outer expandable cage of cells. The designs can feature a constrained delivery configuration and an expanded deployed configuration. An outer cage can have wide opening struts to allow for clot integration into the device. Both the inner body and outer cage can be configured with shapes to pinch a clot in addition to embedding in it. The devices can also be capable of having a portion of the outer cage fold and invert proximally after engaging with a target clot to internalize it. These factors can increase the device's ability to capture clots of all compositions, allowing for safer and more efficient flow restoration.

Fibrin rich / soft clot mechanical thrombectomy device

A clot retrieval device includes an inner expandable member and an outer expandable member, each formed from respective strut frameworks such that the outer expandable member has larger cell openings than the inner expandable member. The outer expandable member can have multiple discontinuous body segments spaced apart in relation to a longitudinal axis of the device. Adjacent discontinuous body segments can be joined by a pair of tapered connecting arms that are able to bend with a small radius of curvature compared to the body segments. Some or all of the body segments can include radiopaque markers positioned to illustrate a circumference of the respective body segment and slightly staggered in relation to a longitudinal axis of the device such that the markers nest when the device is collapsed for delivery.

Growing community of inventors

Galway, Ireland

Declan Lee