Pfizer Corporation

Pharmacia & Upjohn Company

Pah P&u LLC

Debra Ann Sherry

Peter Laurence Toogood

Dennis Joseph McNamara

Michael R Barbachyn

Arthur Glenn Romero

Timothy Allan Johnson

John R Palmer

Alexander Ross Hurd

Lisa Marie Thomasco

Paul Joseph Dobrowolski

J Craig Ruble

Matthew Frank Brown

Clarke Bentley Taylor

Edmund Lee Ellsworth

Joseph Scott Warmus

Sean Timothy Murphy

Denton Wade Hoyer

Manjinder Singh Lall

Charles Francis Donovan

Gordon L Bundy

Donna Lee Romero

Chris Limberakis

Timothy Allen Johnson

Gary E Martin

Gordan L Bundy

Chris Lim-Berakis

Michael Robert Barbachyn

Dennis Joseph Mcnamara

John Raymond Palmer

The invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof, thereof, wherein: and pharmaceutically acceptable salts, prodrugs, hydrates, or solvates, thereof, wherein A, B, L-L, A, B, R-R, and m are as defined herein. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and their use in treating a bacterial infection.

Hydroxamic acid derivatives useful as antibacterial agents

The invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof, thereof, wherein: G is a group of formula (II); and pharmaceutically acceptable salts, prodrugs, hydrates, or solvates, thereof, wherein A, B. L-LA, B, R-Rand m are as defined herein. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and their use in treating a bacterial infection.

The present invention is directed to tricyclic tetrahydroquinoline compounds of formula I, and pharmaceutically acceptable salts thereof wherein the variables R, R, R, R, R, Rand X are as described herein and to pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.

Tricyclic tetrahydroquinoline antibacterial agents

The invention includes tetrahydroquinoline and related compounds of formula I and pharmaceutical compositions thereof, that exhibit useful antibacterial activity again a wide range of human and veterinary pathogens 

Described herein are antibacterial compounds, methods for making the compounds, pharmaceutical compositions containing the compounds and methods of treating bacterial infections utilizing the compounds and pharmaceutical composition.

Antibacterial agents

The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens 

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Chelsea, MI, United States of America

Debra Ann Sherry