Syntex (u.s.a.) Inc.

Deborah L McClelland

Joseph M Muchowski

Lawrence Emerson Fisher

Roberto P Rosenkranz

Edvige Galeazzi

Joan Marie Caroon

Compounds of Formula I ##STR1## in which: R.sub.1 is hydrogen, lower alkyl, --C(O)R.sub.3, or --C(O)NR.sub.3 R.sub.4, where R.sub.3 and R.sub.4 are independently lower alkyl, phenyl, or phenyl lower alkyl;

Bis(benzylpyrrolidine) derivatives useful for treating congestive heart

Compound of Formula I ##STR1## in which: R.sub.1 is hydrogen, lower alkyl, --C(O)R.sub.3, or --C(O)NR.sub.3 R.sub.4, where R.sub.3 and R.sub.4 are independently lower alkyl, phenyl, or phenyl lower alkyl;

Bis(benzylpyrrolidine) derivatives as dopamine agonists

Dopamine agonist compounds disclosed are useful in treating hypertension and congestive heart failure in mammals. The compounds have the following general formula (I) ##STR1## wherein: X is nitrogen or CH;

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Palo Alto, CA, United States of America

Deborah L McClelland