Novartis Ag

Ciba-Geigy Corporation

Deborah Jean Mulcahy

Bernhard Seiferling

John Martin Lally

Friedrich Stockinger

Achim Muller

Roger Biel

Peter Hagmann

Beat Muller

Axel Heinrich

Günter Lässig

Gabriela Cocora

Uwe Haken

Daryl Reece

William Jordan Hall

Honghui Lu

Charlotte Lynn Cooper

Carlton Pope

Yongxing Qiu

Robert Carey Tucker

Robert Allen Janssen

Yeming Gu

Leslie F Stebbins

Jordan Hall

Rebeca Kyker Bowden

Benjamin David Sullivan

Judy L Peeples

There is described a process for manufacturing an ophthalmic lens and an apparatus for forming an ophthalmic lens, in particular a silicone hydrogel contact lens, wherein in a mold assembly a first and a second mold half () are first arranged in an intermediate closed position in which the mold surfaces of the two mold halves are spaced apart from each other at a distance increase (d1) of preferably 1 to 100 &#x3bc;m relative to a final distance (d0) in a final closed position, and wherein, during curing of the lens forming material (), the mold surfaces () of the mold halves () are actively or passively moved or moving from the intermediate closed position to the final closed position, where the distance increase (d1) is 0.

Process for manufacturing an ophthalmic lens

Described herein are methods for imaging ocular devices. The methods generally involve (a) applying a scattering agent to the ocular device; and (b) imaging the ocular device using optical coherence tomography (OCT). The methods described herein provide useful structural information about the surface of the device with high sensitivity.

Methods for imaging ocular devices using optical coherence tomography

There is described a process for manufacturing an ophthalmic lens and an apparatus for forming an ophthalmic lens, in particular a silicone hydrogel contact lens, wherein in a mold assembly a first and a second mold half () are first arranged in an intermediate closed position in which the mold surfaces of the two mold halves are spaced apart from each other at a distance increase (d) of preferably 1 to 100 &#x3bc;m relative to a final distance (d) in a final closed position, and wherein, during curing of the lens forming material (), the mold surfaces () of the mold halves () are actively or passively moved or moving from the intermediate closed position to the final closed position, where the distance increase (d) is 0.

A method of incorporating radiation-absorbing agents (i.e., dyes) into polymeric materials. A preferred method involves crosslinking or polymerizing a polymerizable or crosslinkable material in the presence of a polymeric dye. A preferred product is a tinted contact lens comprising poly(vinyl alcohol). The methods offer advantages in reduced fabrication cycles, reduced extractables, elimination of post-polymerization activation steps, elimination of post-polymerization extraction steps and reduced scrap and costs associated with lens handling.

Method and composition for incorporating radiation-absorbing agents into

A method of incorporating dyes into polymeric materials. The method involved contacting a functionalized dye with a high molecular weight crosslinkable polymer precursor, dispensing the solution into a mold and applying radiation, thereby forming a molded article having dye covalently bonded to the polymer backbone. A preferred product is a visibility tinted disposable contact lens comprising poly(vinyl alcohol). Various embodiments of the innovative method offer advantages in reduced fabrication cycles, reduced extractables, elimination of post-polymerization activation steps, elimination of post-polymerization extraction steps and reduced scrap and costs associated with lens handling.

The invention relates to a process for the manufacture of tinted ophthalmic moldings comprising the steps of

Methods and compositions for manufacturing tinted ophthalmic lenses

A method and composition useful in fabricating radiation-absorbing contact lenses, especially ultraviolet (UV) and visible (tint) light-absorbing lenses. The radiation-absorber is incorporated into a contact lens in the presence of a buffer which maintains the pH near neutral. Subsequently, the radiation-absorber is chemically affixed to the lens by raising the pH to a highly basic level.

Method of increasing the concentration of radiation-absorbing agents in

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Duluth, GA, United States of America

Deborah Jean Mulcahy