Siemens Aktiengesellschaft

Siemens Medical Solutions USA, Inc.

Osram Opto Semiconductors Gmbh

Osram Oled Gmbh

Siemens Healthcare Gmbh

Debora Henseler

Karsten Heuser

Ronald Grazioso

Nan Zhang

Georg Wittmann

Matthias J Schmand

Arvid Hunze

Ralph Paetzold

Jens Fürst

Meinrad Schienle

Hagen Klausmann

Andreas Kanitz

Björn Heismann

Wolfgang Rogler

Daniel Niederlöhner

Jan Birnstock

Sandro Francesco Tedde

Wiebke Sarfert

Peter Hansen

Sanghee Cho

Silke Janssen

Ralph Pätzold

Dirk Buchhauser

Carsten Tschamber

Björn-Oliver Eversmann

Guenter Gieres

Mathias J Schmand

Günter Gieres

Jens FÜRST

A representative positron emission tomography (PET) system includes a positron emission tomography detector having one or more silicon photomultipliers that output silicon photomultipliers signals. The PET system further includes a calibration system that is electrically coupled to the silicon photomultipliers. The calibration system determines a single photoelectron response of the silicon photomultipliers signals and adjusts a gain of the silicon photomultipliers based on the single photoelectron response.

Systems and methods for calibrating a silicon photomultiplier-based positron emission tomography system

A system and method is provided for determining depth of interaction (DOI) information. The system and method includes a detector configured to generate DOI information as a result of radiation emitted from a radiation source. The system and method further includes a plurality of scintillator pixels forming a block, wherein the plurality of scintillator pixels have a first portion and a second portion. A first medium distributed in an alternating pattern of coupling and separation between each of the scintillator pixels in a first portion or second portion of the block is also provided. A plurality of sensors for detecting scintillation events across the plurality of scintillators based on the alternating pattern of coupling and separation between each of the scintillator pixels, wherein DOI information is provided by a position profile of the block, and an image processor for generating a 3 dimensional image from the DOI information are also included.

System and method for providing depth of interaction detection using positron emission tomography

Forming an arrangement of two ceramic barrier layers () on a polymeric substrate () includes the steps of applying a first ceramic barrier layer () on the substrate (). The surface (A) of the first barrier layer () is modified to introduce new nucleation sites on the surface of the first layer. A second ceramic barrier layer () is formed on the first barrier layer () using the new nucleation sites. The second ceramic barrier layer is deposited with independent nucleation sites such that a barrier stack of enhanced quality is formed.

Ceramic barrier layers

A high-resolution nuclear imaging detector for use in systems such as positron emission tomography includes a monolithic scintillator crystal block in combination with a single photomultiplier tube read-out channel for timing and total energy signals, and one or more solid-state photosensor pixels arrays on one or more vertical surfaces of the scintillator block to determine event position information.

Positron emission tomography detector based on monolithic scintillator crystal

A system and method are provided for determining the onset of gamma interactions for positron emission tomography (PET) imaging more accurately than with existing techniques. The timing of a sequence of primary trigger events is obtained and used to determine a weighted combination, which mixes the timing information from the various primary trigger events to compute an overall event trigger timing with improved time resolution. Numerical simulations demonstrate that the invention improves time resolution by approximately 10% over state-of-the-art methods. This improved time resolution directly benefits the imaging performance of the PET scanner, especially in time-of-flight (TOF) mode, where a high time resolution directly translates to a reduction in image noise at the same dose&#x2014;or, alternatively, a reduction of dose to the patient or scan time for the same image quality.

System and method for improving detection of gamma interactions in a positron emission tomography system

The invention relates to an organic-based electronic component, especially a component with reduced pixel crosstalk. According to the invention, the crosstalk is reduced by a grid electrode.

Organic-based electronic component containing pixels

The invention provides a Silicon Photomultiplier (SiPM). The SiPM includes a plurality of microcells, a nonlinear element integrated in each one of the plurality of microcells, and a trigger line for outputting a summated current of the plurality of microcells, wherein the nonlinear element provides for a separated timing and energy signal.

Device having a plurality of photosensitive microcells arranged in row or matrix form

Systems and methods of generating timing triggers to determine timing resolutions of gamma events for nuclear imaging includes receiving a pulse signature representing a succession of triggers associated with a photomultiplier. When a number of triggers occurring within a predetermined time interval matches a predetermined number, an event trigger can be initiated. A delayed version of the pulse signature can be generated and compared to a predetermined timing trigger level. When the delayed version matches the predetermined timing trigger level, a timing trigger can be generated. Based on the timing trigger level, the timing trigger can be generated at the pulse of the delayed version that corresponds to the first photoelectron of a gamma event. The timing trigger can correspond to a timestamp for the first photoelectron so that a data acquisition system can identify the pulse from which to acquire energy information to generate a nuclear image.

System and method of determining timing triggers for detecting gamma events for nuclear imaging

Systems and methods for correcting output signals from non-linear photosensors, specifically silicon photomultipliers (SiPMs). SiPMs are used in a PET detector to readout light emissions from LSO scintillator crystals. The non-linear output of the SiPM can distort and compress the energy spectrum which is crucial in PET imaging. The non-linearity effect for inter-crystal scattered events can place an energy event outside of the PET detector energy window, resulting in a rejected event. Systems and methods to correct the SiPM non-linearity for inter-crystal scattered events, so as to be able to obtain the proper energy event and produce an accurate medical image, are disclosed.

Energy correction for one-to-one coupled radiation detectors having non-linear sensors

An apparatus and method to decrease light saturation in a photosensor array and increase detection efficiency uses a light distribution profile from a scintillator-photodetector geometry to configure the photosensor array to have a non-uniform sensor cell pattern, with varying cell density and/or varying cell size and shape. A solid-state photosensor such as a SiPM sensor having such a non-uniform cell structure realizes improved energy resolution, higher efficiency and increased signal linearity. In addition the non-uniform sensor cell array can have improved timing resolution due to improvements in statistical fluctuations. A particular embodiment for such photosensors is in PET medical imaging.

Providing variable cell density and sizes in a radiation detector

The invention relates to an organic light-emitting diode (OLED) having an improved lifetime and improved transport of negative charge carriers. The organic light-emitting diode is based on an organic semiconductor material, in which the transport of negative charge carriers and stability with respect to reduction is achieved with triarylated Lewis acid units, in particular perarylated borane units. This leads to an improved lifetime of the emission layer which in turn increases the lifetime of the component and eliminates the need for correcting brightness during operation. Furthermore, the invention relates to organic light-emitting diodes in which the position of the emission zone in the emitter layer and the color of the emission can be influenced in a targeted manner through triarylated Lewis acids such as perarylated borane units.

Organic light-emitting diode and uses thereof

Presented an organic light-emitting device (OLED) that includes at least one active region, at least one organic layer, a first glass plate on which the at least one active region is applied, and a second glass plate. The active region is disposed between the first and the second glass plates. The first and second glass plates are at least partially transparent in the near infrared spectral range. The OLED further includes a bonding material that includes a solder glass and is disposed between the first and second glass plates. The bonding material forms at least one frame that surrounds the active region and mechanically connects the first glass plate with the second glass plate and seals the active region. The bonding material absorbs near infrared radiation. The OLED further includes spacer particles that have a mean diameter that maintains a height between the first and second glass plates.

Encapsulation of organic devices

The present invention is a Silicon PhotoMulitplier comprising a plurality of photon detection cell clusters each comprising a plurality of avalanche photodiodes connected in parallel, so that the output of each avalanche photodiode is summed together and applied to a cell cluster output. Each of the plurality of cell cluster outputs is connected to one of a plurality of cluster readout circuits, each of which includes an analog to digital converter that converts an analog representation of the total energy received by a photon detection cell cluster to a digital energy signal. A SiPM Pixel reader circuit is connected to the plurality of cluster readout circuits and configured to generate an overall pixel output by digital processing the plurality of digital energy signals received from the plurality of photon detection cell clusters by way of the plurality of cluster readout circuits. The SIPM pixel reader circuit also receives digital signals representative of timing triggers and the total energy received by a specific photon detection cell cluster and generates an overall SiPM energy signal and overall timing trigger in response to the signals received from the plurality of cluster readout circuits.

SiPM photosensor with early signal digitization

A flat organic photodetector has a structured first electrode that forms several sub-electrodes, a second electrode, at least one first organic layer, and a second organic layer. The organic layers are situated between the two electrodes and are structured in conformity with the structuring of the first electrode, so that the two organic layers are subdivided into multiple active regions respectively corresponding to the sub-electrodes of the first electrode. An x-ray detector has such a flat organic photodetector and an x-ray absorbing layer applied thereon.

Photodetector, flat X-ray detector and method for producing the same

An encapsulation for an organic electronic component, characterized in that the component, encapsulated in a dimensionally stable capsule, is at least partially covered with a protective film.

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Erlangen, Germany

Debora Henseler