Applied Biosystems, LLC

USA as Represented by Secretary of the Navy

The University of Texas System

Life Technologies Corporation

Debjyoti Banerjee

Charles Stuart Vann

James C Nurse

Timothy G Geiser

Nigel P Beard

Jun Xie

Umberto Ulmanella

Konrad Faulstich

Aldrich Lau

Aldrich N K Lau

Ryan P Lu

Seunghwan Jung

Christopher K Huynh

Jiwon Yu

Ayax D Rammirez

Donghyun Shin

Saeil Jeon

Seokwon Kang

Byeongnam Jo

A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting.

Electrowetting dispensing devices and related methods

Systems and methods for forming nanoparticles in-situ are disclosed herein. The nanoparticles may be formed in-situ through thermocycling a solution comprising at least one of a molten salt, a surfactant, and a catalyst. The nanoparticles may form in the solution itself and/or on surfaces of a vessel in which the solution is formed. Nanofins may be formed from the agglomeration of particles in the solution and on surfaces. Microchannels may be formed by these nanofins, and in some cases microchannels on a surface may have nanofins form on the surface. In some embodiments, a previously formed solution that has nanoparticles formed in-situ may be used to generate nanofins in a vessel, on a wafer in a vessel, in the solution itself, or combinations thereof.

Systems and methods for in-situ formation of nanoparticles and nanofins

A device having a first substrate and a second substrate separated from the first substrate to form a volume between the first and second substrates, electrodes disposed on the first and second substrates and facing the volume, each substrate comprising at least one electrode, and a first insulating layer disposed on the first substrate and a second insulating layer disposed on the second substrate to separate the electrodes from the volume.

A method of liquid phase synthesis of carbon nanotubes in air comprising the steps of making a first liquid phase metal salt catalyst solution of a first predetermined volume; making a carbon source liquid phase solution of a second predetermined volume; ultrasonicating the first metal salt catalyst and the carbon source solutions to de-agglomerate and uniformly disperse their powder form into the solutions; depositing predetermined volumes of droplets of the first metal salt catalyst and the carbon source solutions onto a substrate; drying the first metal salt catalyst and the carbon source solutions on the substrate in an air environment for a predetermined time to form a carbon and catalyst composite; and heating the carbon and catalyst mixture in the air environment for a predetermined temperature and time to form one or more carbon nanotubes.

Method of liquid phase synthesis of carbon nanotubes in air

A diagnostic device is provided that includes a plurality of retainment regions interconnected through at least one fluid processing passageway or separated by at least one barrier. A fluid flow modulator can be provided in the fluid processing passageway if a fluid processing passageway is provided. The barrier and/or fluid flow modulator can comprise a polysaccharide, a derivative of a polysaccharide, or a combination thereof. For example, the barrier can comprise a chitosan material.

Fluid processing device including size-changing barrier

A diagnostic device is provided that includes a plurality of retainment regions, with the retainment regions that are separated by at least one dissolvable barrier. The retainment regions can be interconnected through at least one fluid processing passageway. A retainment region can include a container such as a retainment region, well, chamber, or other receptacle, or a retainment region such as a surface on which the material is retained. The retainment regions can include a reaction retainment region, one or more reagent retainment regions, each containing unreacted reagents, and a sample retainment region. A pressure-actuated valve can be positioned in each fluid processing passageway interconnecting the one or more reagent retainment regions with the respective intermediate retainment regions interposed between each of the one or more reagent retainment regions and the reaction retainment region. The dissolvable barrier can be a fluid flow modulator in the at least one fluid processing passageway.

Microfluidic device including a dissolvable structure for flow control

A fluid processing device is provided that includes a substrate, a plurality of fluid retainment regions formed in or on the substrate, and a barrier at least partially separating two or more of the fluid retainment regions. The barrier includes a mixture of a sequestering material and a reaction component. The reaction component can be at least one of a reactant, a reagent, a catalyst, an initiator, a promoter, a cofactor, an enzyme, a salt, or a combination thereof. The sequestering material can be a porous material, a dissolvable material, or both.

Fluid processing device including composite material flow modulator

Growing community of inventors

College Station, TX, United States of America

Debjyoti Banerjee