Genetic Technologies Limited

Debbie Mantzaris

Eduardo Vom

Richard Allman

Craig Matthew Lewis

Nicola Charlotte Andrews

Denis Greco

David Jonathan Sparling

Stuart Cantsilieris

Maria Luisa Ashdown

The present invention relates to a method of enriching fetal nuclei from a sample. Enriched fetal nuclei can be used in a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing.

Methods for obtaining fetal genetic material

A sampling device adapted for transcervical sampling of biological materials from a pregnant patient comprising: an elongate insertion tube () having a first end () adapted for insertion through the external orifice (external os) of said patient's cervix and a second end () including a handle means () for manipulating said tube; a measuring means for determining the position of said first end of said tube within said cervix, wherein said first end () includes a sampling head () adapted to collect biological material including cells, mucus and biological fluids, and wherein said measuring means is adapted to determine the extent of insertion and transcervical position of said first end to optimize the transcervical sampling site.

Biological sampling device

A sampling device adapted for transcervical sampling of biological materials from a pregnant patient comprising:

Embodiments relate generally to a sampling device adapted for sampling of biological materials from a subject and methods of use or manufacture of such devices, as well as diagnostic methods employing such devices and kits including such devices. The sampling device may comprise: an outer tube; an elongate insertion member having a first end and a second end, wherein the first end is distal of the second end, the insertion member being received in and sized to be movable through the outer tube; a coupling portion disposed at the first end of the insertion member; and a sampling portion coupled to the coupling portion and configured to collect the biological materials. The coupling portion is separable from the insertion member.

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Avondale Heights, Australia

Debbie Mantzaris