Boston Scientific Scimed, Inc.

Deanna Cavallaro

Mark W Boden

Sandra Nagale

Timothy Paul Harrah

Steven L Kangas

Kasyap Venkata Seethamraju

Yitzhak Mendelson

Jonathan Zoll

Glenn R Gaudette

Martin Phelan

David Shreeve

Tristan Richardson

Tyler Hickey

Rami Shuraim

Dervis Goksun

The present disclosure relates to the field of tissue mapping and ablation. Specifically, the present disclosure relates to expandable medical devices for identifying and treating local anatomical abnormalities within a body lumen. More specifically, the present disclosure relates to systems and methods of focal treatment for overactive bladders.

Systems and methods for mapping and ablation in the bladder

Methods of treating tissue of a patient, e.g., tissue of an organ such that the bladder, are described. The methods may comprise inserting a medical device within the bladder; and injecting a composition to separate a first layer of tissue from a second layer of tissue. The composition may comprise at least one polysaccharide compound having a concentration ranging from approximately 0.05% to approximately 25% by weight, with respect to the total weight of the composition. The composition may at least partially separate the first layer of tissue from the second layer of tissue. At least one of the first layer of tissue or the second layer of tissue may be a detrusor muscle tissue.

Compositions and methods for treatment of tissue

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Medford, MA, United States of America

Deanna Cavallaro