University of Michigan

Berry and Associates, Inc.

Glen Research Corporation

Dean S Wise

Leroy B Townsend

Anthony Denver Sercel

David A Berry

Hugh Mackie

Kee-Yong Jung

John B Randolph

Robert L Somers

Siya Ram

A fluorescent nitrogenous base and nucleosides including the fluorescent nitrogenous base are provided. Nucleosides including the fluorescent nitrogenous base are capable of Watson-Crick base pairing with naturally occurring nucleosides. The nucleosides including the fluorescent nitrogenous base have many uses including but not limited to use in probes, in the synthesis of nucleic acids, and in investigating nucleic acid interactions with other nucleic acids and/or with proteins.

Fluorescent nitrogenous base and nucleosides incorporating same

Soluble alkyl [5-(amino (phenyl)methyl)-2H-benzimidazol-2-yl]carbamates, their enantiomorphic forms, and acid addition salts thereof are well absorbed and possess curative anthelmintic activity, especially against filarial worms, when administered orally or parenterally. Pharmaceutical compositions containing the compounds and methods of employing the compounds in methods of treating helminth infections in mammals are also disclosed, together with methods of synthesis.

Soluble alkyl[5-[amino (phenyl)methyl]-1H-benzimidazol-2-yl] carbamate

Growing community of inventors

Ann Arbor, MI, United States of America

Dean S Wise