Other

Genetics Institute, Inc.

Dean M Toriumi

Elizabeth A Wang

Josephine S D'Alessandro

A nose clip includes an outer support member adapted to contact an outside surface of a nose; a bridge connected at a first end to the outer support member; and an inner support member connected to a second end of the bridge and adapted to be inserted into the nostril and to contact an inner surface of the nostril. When inserted, tension generated between the outer support member and the inner support member causes lateral movement of a surface within the nostril and opens a nasal airway. Additionally, the inner support can be curved to create an outward movement of the lateral wall of the nose. This in turn enables improved breathing. The nose clip may be made of a malleable material. The inner support member may include extensions that are malleable. The inner support members may be bent so that they create a convex contour of an interior surface of the nasal cavity. A different embodiment of the nose clip can be used to deliver drugs via a fluid filled cavity and porous surface that allows evaporation of the fluid and drug into the nasal cavity as air is drawn over the inner support member.

Nose clip

A nose clip includes an outer support member adapted to contact an outside surface of a nose. A bridge connected at a first end to the outer support member; and an inner support member connected to a second end of the bridge and adapted to be inserted into the nostril and to contact an inner surface of the nostril. When inserted, tension generated between the outer support member and the inner support member causes lateral movement of a surface within the nostril and opens a nasal airway. Additionally, the inner support can be curved to create an outward movement of the lateral wall of the nose. This in turn enables improved breathing.

Methods and devices are disclosed for inducing growth of neural cells, and repairing neural defects in a mammal. The method comprises administering to said mammal at the site of neural defect, damage or depletion, an effective amount of a bone morphogenetic protein, either in admixture with a pharmaceutically acceptable vehicle, or adsorbed to a suitable matrix. The device comprises bone morphogenetic protein, optionally in combination with other factors, adsorbed on a suitable matrix and contained within an artificial nerve replacement vessel.

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Riverside, IL, United States of America

Dean M Toriumi