Beckman Coulter, Inc.

Dean G Binger

Hashem Akhavan-Tafti

Renuka De Silva

Wenhua Xie

Michael Salvati

James D Mendoza

Bruce H Odegaard

Ying Chen

Nir Shapir

Terri McLernon

Methods, reagents, kits and systems are disclosed for determining an analyte in a sample suspected of containing the analyte where all reagents are soluble in aqueous solution. One assay method includes treating a sample suspected of containing the analyte under conditions such that if the analyte is present, an activator is brought into reactive configuration with a chemiluminescent compound to activates it. The sample is also treated with an agent to reduce signal not related to analyte. Finally, the sample is treated with a trigger solution thereby producing light from the activated chemiluminescent compound. No reagents are associated with a surface or other solid phase.

Solution phase homogeneous assays

Growing community of inventors

St. Louis Park, MN, United States of America

Dean G Binger