The United States of America, As Represented by the Secretary, Department of Health and Human Services

Dean D Erdman

Larry J Anderson

Thomas G Ksiazek

Anthony Sanchez

Pierre E Rollin

Cara Carthel Burns

Raymond Campagnoli

William Allan Nix

M Steven Oberste

Paul A Rota

Mark A Pallansch

Suxiang Tong

James A Comer

Cynthia Goldsmith

Stephan S Monroe

William J Bellini

Xiaoyan Lu

Shannon L Emery

Charles D Humphrey

Joseph P Icenogle

Teresa C T Peret

Sherif R Zaki

Qi Chen

Byron T Cook

Jeanette Guarner

Richard F Meyer

Christopher D Paddock

Wun-Ju Shieh

Michael D Bowen

A process for detecting human rhinovirus nucleic acid in a biological sample, includes producing an amplification product by amplifying an human bocavirus nucleotide sequence using a forward primer of SEQ ID NO: 1, and a reverse primer of SEQ ID NO: 2, and measuring said amplification product to detect human rhinovirus in said biological sample. Also provided are reagents and methods for detecting and distinguishing human rhinovirus from other viruses. A kit is provided for detecting and quantifying human rhinovirus in a biological sample.

Selective detection of human rhinovirus

Disclosed herein is a newly isolated human coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome (SARS). Also provided are the nucleic acid sequence of the SARS-CoV genome and the amino acid sequences of the SARS-CoV open reading frames, as well as methods of using these molecules to detect a SARS-CoV and detect infections therewith. Immune stimulatory compositions are also provided, along with methods of their use.

Coronavirus isolated from humans

Growing community of inventors

Decatur, GA, United States of America

Dean D Erdman