Natural Pharmacia International, Inc.

Other

Research Triangle Institute

Research Triangle Research North Carolina

David Yue-wei Lee

C Edgar Cook

John A Kepler

Gary S Bartley

Rupa S Shetty

Amir H Rezvani

James A Raleigh

Rui-Lin Li

Qi-Lu Cheng

Yue-Hu Pei

David Overstreet

Younki Kho

A space adjustable rack for storing fragile wine/Champaign/cocktail glasses during transportation and for storing the glasses in house is provided. The space adjustable precious alcohol beverage glass storing rack can hold glasses of different sizes at the same time. The rack of the current application is comprised of a bottom structure, pluralities of latitudinal spacing blades, and pluralities of longitudinal spacing blades. The space adjustable rack protects those wine/Champaign/cocktail glasses from severe vibration impact caused by earthquake and transportation.

Space adjustable rack for cocktail glasses to endure earthquake

The invention is directed to a novel class of steroids which exhibit potent antiprogestational activity.

17.beta.-nitro-11.beta.-arylsteroids and their derivatives having

The invention is directed to 11.beta.-arylsteroids of formula II: ##STR1## wherein R.sup.1, R.sup.6, R.sup.8, R.sup.12 and X are as defined by the specification. The compounds exhibit potent antiprogestational activity and are useful in the treatment of fibroids, endometriosis, cervical ripening prior to delivery, hormone replacement therapy and in the control of fertility.

17.beta.-nitro-11.beta.-arylisteroids and their derivatives having

The invention is directed to 17.beta.-nitro-11.beta.-arylsteroids of formula I: ##STR1## wherein R.sup.1, R.sup.6, R.sup.7, R.sup.12 and X are as defined by the specification. The compounds exhibit potent antiprogestational activity and are useful in the treatment of fibroids, endometriosis, cervical ripening prior to delivery, hormone replacement therapy and in the control of fertility.

Isoflavonoids containing a carbon-carbon linked .beta.-D-glucose moiety at the C-8 position and isolated from the Chinese herbal plant Pueraria lobata are useful for treating alcohol dependence.

Method for treating alcohol dependence

Derivatives of 2-nitro-imidazole, such as 1-(2-hydroxy-3-piperidinopropyl)-2-nitro-imidazole, are useful as hypoxic cell markers for immunochemical detection of hypoxia in tumor tissue.

Derivatives of 2-nitro-imidazoles as hypoxic cell markers

A-Nor-5.alpha.-androstane compounds, such as the dipropionate and disuccinate esters of 2.alpha.,17.alpha.-diethynyl-A-Nor-5.alpha.-androstane-2.beta.,17.beta.-di ol and the corresponding 2.alpha.,17.alpha.-diol stereoisomers have an inhibitory effect on malignant cell growth and can be used to treat various carcinomas in mammals.

Use of A-Nor-steroids as malignant cells growth inhibitors

A high speed countercurrent centrifuge is designed so that the chromatographic column used therewith may be readily replaced. A shaft for rotating a chromatographic column includes a column holder plate fixed therearound. The column holder plate has upwardly extending pins which engage the corresponding holes on the bottom flange of a spool about which a chromatographic column is wrapped, fixing the orientation of the spool relative to the column holder plate. Also a multi-layer chromatographic column is constructed to be used in the centrifuge. Multiple layers of tubing are wrapped around the above-described spool. The inlet and outlet ends of this tubing terminate in tubing adaptors mounted on an outer surface of a flange to permit quick connection of the column to the flow tubes of the centrifuge apparatus.

Growing community of inventors

Chapel Hill, NC, United States of America

David Yue-wei Lee