Abbvie Stemcentrx LLC

Protagonist Therapeutics, Inc.

Biological Dynamics, Inc.

Stemcentrx, Inc.

Scios Inc.

Other

Rmg Networks, Inc.

Fibrogen, Inc.

Toshiba International Corporation

Asher Biotherapeutics, Inc.

Raytheon Company

Cetus Corporation

Utility Trailer Manufacturing Company

Global Eagle Entertainment Inc.

Protaganist Therapeutics, Inc.

David Y Liu

Laura Saunders

Orit Foord

Robert A Stull

Scott J Dylla

Michael Torgov

Hui Shao

Ashok Bhandari

Robert Paul Turner

Rajaram Krishnan

Paul David Swanson

Eugene Tu

Kai Yang

David Jean Charlot

James McCanna

Irina V Dobrovolskaya

Lucas Kumosa

Brian Troy Frederick

Dinesh Vinoobhai Patel

John A Lewicki

George Frederic Schreiner

Gregory Thomas Bourne

Jie Zhang

John J Perumattam

Babu J Mavunkel

Larry C Mattheakis

Xiaoli Cheng

Sarvajit Chakravarty

Sundeep Dugar

Genet Zemede

Juan Pablo Hinestrosa Salazar

Deepti Rokkam

Mark Douglas Rayner

Monette Aujay

Kurt Allen Bihler

Juscilene Menezes

R Richard Goehring

Stephen J Klaus

Todd W Seeley

Mark Leslie Smythe

Yik Andy Yeung

Sampath Kumar Anandan

Alex Bankovich

Johannes Hampl

Ivana Djuretic

Henry C Nguyen

Mandy Boontanrart

Zehra Kaymakcalan

Roopa Taranath

Adam Stephenson

Renee L Greer

Byong Kang

Jun Liu

Terrence Chen

Benjamin S Pollack

Yao-Jen Chang

Andrew Asher Protter

Thomas B Neff

Wen Wu

Ingrid Langsetmo Parobok

Gregory R Luedtke

L L Houston

William Usinger

Qingjian Wang

Marianne Theresa Santaguida

Noelynn A Oliver

Robert Kovelman

Kenneth S Komisarek

Anoop K Sinha

Mukund M Mehrotra

James M Warwick

Christopher T Jacob

Allan Flyvbjerg

Guangjie Guo

Iryna Clark

Patrick O'Connor

Julia Gavrilyuk

Gregory Leudtke

Alexander Schammel

Kirsten Mundy

Paul Anthony Escarpe

William Robert Arathoon

Ishai Padawer

Luis Antonio Cano

John Yorko

Vikram Natwarsinhji Sisodiya

Karthik Narayan Mani

Sheila Bheddah

Javier Lopez-Molina

Robert Turner

James Mccanna

Irina Dobrovolskaya

Paul Swanson

David Charlot

Todd A Seeley

The present disclosure provides methods and compositions comprising IL-21 polypeptides, targeted cytokine construct that selectively activates target immune cells (e.g., CD8+ T cells) over other immune cell types. The cytokine of the present disclosure can further comprise mutations that alter its charge distribution to improve its half-life within the blood.

IL-21 polypeptides and targeted constructs

The present invention provides hepcidin analogues with improved in vivo half lives, and related pharmaceutical compositions and methods of use thereof.

Conjugated hepcidin mimetics

Peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel disease, are disclosed.

Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases

The invention relates to thioether monomer and dimer peptide molecules which inhibit binding of &#x3b1;4&#x3b2;7 to the mucosal addressing cell adhesion molecule (MAdCAM) in vivo.

&#x3b1;4&#x3b2;7 thioether peptide dimer antagonists

A demand-based load balancing function may be provided by one or more drive controllers that takes advantage of the affinity laws to linearize the control of the variable of interest (e.g., flow, pressure, etc.). Each drive controller may be set up by the user simply inputting a few values into the drive controller. Based on the inputs, the drive controllers may interpolate control points using an assumed linear relationship between the variable to be controlled (e.g., pressure) and the current driven to the pump. Feedback data from the system may be used to continually update the drive controllers so as to potentially allow them to better balance power usage to each pump.

Pump system control

Linear pump control

Phased array antenna systems with antenna elements having substrates with varying dielectric constants selected to reduce the self-return signal of corner elements in the array. In one example, a phase array antenna system includes a plurality of stacked-patch microstrip antenna elements arranged in a two-dimensional array, each stacked-patch microstrip antenna element of the plurality of stacked-patch microstrip antenna elements including a pair of conductive patches disposed above a ground plane on a dielectric substrate. The dielectric substrate of corner stacked-patch microstrip antenna elements in the array has a dielectric constant lower than a dielectric constant of the dielectric substrate of non-corner stacked-patch microstrip antenna elements in the array.

Phased array antenna with edge-effect mitigation

The invention relates to peptide dimer compounds and peptide monomer compounds that potently inhibit binding of &#x3b1;4&#x3b2;7 to the mucosal addressin cell adhesion molecule (MAdCAM) in vivo, possess high selectivity against &#x3b1;4&#x3b2;1 binding, and have high stability under gastrointestinal conditions.

&#x3b1;4&#x3b1;7 peptide monomer and dimer antagonists

Provided are novel anti-SEZ6 antibodies and antibody drug conjugates, and methods of using such anti-SEZ6 antibodies and antibody drug conjugates to treat cancer.

Anti-SEZ6 antibody drug conjugates and methods of use

Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.

Light chain variable regions

Systems, devices, media, methods, and kits are disclosed to integrate and exchange information of analyte analysis kits. Analyte analysis can be performed and presented using in association with advertising or questions.

Methods and systems for analyte information processing

Peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel diseases, are described.

Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases

Growing community of inventors

Palo Alto, CA, United States of America

David Y Liu