Natera, Inc.

Xerox Corporation

Bretford Manufacturing, Inc.

Incase Designs Corp.

Tektronix, Inc.

Palo Alto Research Center Inc.

3d Systems, Inc.

Mophie Inc.

Invisionapp Inc.

Huntsman Advanced Materials Americas LLC

Tekronix, Inc.

Solarsynthesis

David Walter Johnson

Sarah Akin

Matthew Rabinowitz

Zachary Demko

Milena Banjevic

Joshua Sweetkind-Singer

Dusan Kijacic

Dimitri Petrov

Jing Xu

Markus Peter Diebel

Brent Rodney Jones

Gerard H Rousseau

John Albert Wright

Timothy Carlyle Shaw

John Wai Fong

Larry Eugene Hindman

Jamie Kelso

Hubert Benjamin Ki Durn Ng

Eric J Shrader

Daniel Clark Park

Timothy L Crawford

Jeffrey Russell Kohne

Richard Brzezinski

Jonathon Wilson

João Portela

Todd A Eiles

Michael S Allen

Max Nunes

Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment, the chromosome copy number can be determined from the measured genetic data, with or without genetic information from one or both parents.

System and method for cleaning noisy genetic data and determining chromosome copy number

A system and method for determining the genetic data for one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available, are disclosed. Genetic data for the target individual is acquired and amplified using known methods, and poorly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related subjects. In accordance with one embodiment of the invention, incomplete genetic data is acquired from embryonic cells, fetal cells, or cell-free fetal DNA isolated from the mother's blood, and the incomplete genetic data is reconstructed using the more complete genetic data from a larger sample diploid cells from one or both parents, with or without genetic data from haploid cells from one or both parents, and/or genetic data taken from other related individuals.

System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals

A method including combining multiple mutations of a document into a mutation cluster based on a contextual purpose for the mutations is provided. The method includes forming a proposal for modifying the document based on the mutation cluster, transmitting the proposal to a server for validation, storing the proposal in a proposal log when the server validates the proposal, and redoing or undoing the mutation cluster on the document upon an input from a user. A system and a non-transitory storage medium including instructions to perform the above method are also provided.

Persistence strategy for applications

A method including receiving, in a server, a first proposal for modifying a document from a user in a first client device, is provided. The document is a collaboration between users hosted by the server, and includes evaluating the first proposal in view of a second proposal selected from a proposal queue that stores multiple proposals from the users, converting the first proposal into a fact when no conflict is identified between the first proposal and the second proposal, and updating a fact sequence in a fact history log to include the fact. The method also includes providing the fact sequence to the first client device for executing at least a portion of the sequence of documented actions. A system and a non-transitory, computer readable medium storing instructions to perform the above method are also provided.

Collaboration synchronization across devices

Umbrella with solar panels

A solar-powered umbrella has a cap structure that is connected by hinges to struts. The struts are relatively rigid and positioned above the umbrella shade and house solar panels. When the umbrella is opened and closed, the struts rotate via the hinges from an open to closed position. When the solar panels are exposed to the sun, light is converted to electrical energy to charge a rechargeable battery. The battery supplies power to one or more USB ports. A user can recharge an electronic device (e.g., smartphone or tablet computer) by connecting to a port of the umbrella using a cable.

Solar-powered charging umbrella with USB ports

A solar power conversion kit allows converting of a standard umbrella into a solar charging umbrella, which can then use solar power to charge electronic devices. The solar charging umbrella is self-sustained, capable of charging electronic devices in locations away from electrical outlets. The umbrella has a rechargeable battery that is recharged by sunlight. When charged, the umbrella's battery can charge devices when sunlight is not available. The umbrella supports simultaneous charging of higher power devices such as tablet computers.

Solar power conversion kit for umbrella

Growing community of inventors

Tigard, OR, United States of America

David Walter Johnson