Scientific Pharmaceuticals, Inc.

Blendax-werke R. Schneider & Co.

Lee Pharmaceuticals, Inc.

Omnii Oral Pharmaceuticals

Sankin Industries, Ltd.

Scientific Pharmaceutical, Inc.

David V Butler

Jan A Orlowski

Patrick D Kidd

Jeffrey R MacDonald

Amy P Noss

Helmar R Wagner

Lindsay K McKinley

Mahin Mapar

Marvin N Stark

Karla S Somerville

Alice Chin

Disclosed herein are dental temporary filling material and cement formulations comprising a hydrophobic matrix of a hydrophobic material in which an inorganic hardening material and fine, hydrophilic, water-insoluble solid particles are dispersed. The hydrophilic particles serve to conduct water into the hydrophobic matrix to increase the depth and degree of cure in the oral environment as compared to a similar or substantially identical formulation lacking said hydrophilic component.

Saliva-cured dental restorative material

Disclosed herein are acrylic and methacrylic acid ester-based polymeric materials containing as flexibilizing and brittleness reducing agents 1-60% of C-Cpolyalkylene or polyalkyldiene compounds, preferably having a molecular weight of 300-2100, and the use of such materials in dentistry and medicine.

Dental prosthetics comprising curable acrylate polymer compositions and methods of their use

Disclosed are dental varnishes comprising reaction products of rosins with polyalcohols dissolved in mixtures of C-Calcohols with C-Chydrocarbons or C-Chydrocarbons alone which have been found effective in preventing tooth decay and alleviating tooth sensitivity. Such varnishes may, optionally, incorporate therapeutic, antimicrobial and sensory enhancing ingredients.

Caries preventive desensitizing and fluoridizing dental varnishes

Disclosed are dental varnishes comprising reaction products of rosins with polyalcohols dissolved in mixtures of C-Calcohols with C-Chydrocarbons which have been found effective in preventing tooth decay and alleviating tooth sensitivity. Such varnishes may, optionally, incorporate therapeutic, antimicrobial and sensory enhancing ingredients.

Disclosed is a process and composition for bleaching teeth made up of two components blended together before each application. The method and composition offers faster results while significantly reducing the possibility of user discomfort. One of said components comprises carbamide peroxide, the other contains salts and hydroxides and/or oxides of metals belonging to the first or second group of the Periodic Table which stimulate the generation of radical oxygen. In one embodiment, the first part comprises up to 50% water by weight and optionally comprises a stabilizer. In some embodiments, the first component is substantially colorless and the second component comprises a dye indicator which discolors or loses color when exposed to radical oxygen generated by the mixing of the two components.

Process and composition for high efficacy teeth whitening

Described herein is a novel teeth whitening chewing gum formulation comprising bivalent metal peroxide(s) and anhydrous organic acids. Upon mastication in the oral environment, the acids react with the peroxide to form hydrogen peroxide in situ, in an environment stimulating the decomposition of such peroxide to form water and radical oxygen. The system is characterized by its efficacy and convenience. The teeth whitening composition of the preferred embodiment is also virtually insensitive to storage conditions, allowing for an extended shelf life.

Teeth whitening composition in the form of a chewing gum

Described herein is a novel high efficiency teeth bleaching system based on thesynergetic action of the combination of hydrogen peroxide (in a free form or in the form of its adduct with urea) and peroxide and/or percarbonates of metals belonging to the first or second group of the periodic table. In one embodiment, the system of the preferred embodiment comprises two components, one containing hydrogen peroxide or carbamide peroxide (hydrogen peroxide/urea adduct), and the other containing metal peroxides and/or percarbonates. Mixing of the two components results in the accelerated generation of radical oxygen, which relates to faster teeth bleaching action.

Two-part composition for high efficacy teeth whitening comprising a mixture of peroxides and/or percarbonates of metals

Disclosed are compositions for bleaching teeth comprising at least two parts blended together before each application. The compositions offer extended shelf life and accelerated bleaching action while significantly reducing the possibility of user discomfort. In preferred embodiments, one part of the composition comprises peroxides of monovalent or bivalent metals such as sodium, potassium, magnesium, calcium, strontium, and zinc, and another part comprises an aqueous solution of one or more acids able to convert said metal peroxides into hydrogen peroxide, such reaction occurring under conditions resulting in the acceleration of the generation of radical oxygen and, consequently, the teeth whitening process. The inventive compositions allow for adequate water in the composition to avoid tissue desiccation and associated user discomfort without compromising the shelf life of the composition.

Teeth whitening composition with increased bleaching efficiency and storage stability

A process and composition for bleaching teeth made up of two formulations blended together before each application. The invention offers faster results while significantly reducing the possibility of user discomfort. One of said formulations contains hydrogen peroxide (in a free form or in the form of an adduct), the other contains salts and hydroxides and/or oxides of metals belonging to the first or second group of the Periodic Table which stimulate the generation of radical oxygen. The invention allows for balancing pH and assuring adequate water concentration to avoid tissue desiccation and user discomfort without compromising shelf life of the device.

A one-component paste-consistency dental material which cures upon contact with oral fluids intended primarily for use as a temporary restorative/cement. The formulation includes solid particles reactive with water dispersed in a hydrophobic viscous binder which, upon exposure to moisture, will solidify to a depth in excess of 8 mm measured from the surface/water contact area. The curing mechanism relies on both formation of hydrates and reaction of organic polyacids with alkaline glass or metal oxides, or the salts of metal oxides with weak acids. The resulting cured material is non toxic, resistant to deterioration in oral fluids, possesses adequate water resistance, and, optionally, may release fluoride desirable for prevention of secondary decays and alleviation of postoperative tooth sensitivity.

Saliva cured one component dental formulations

A two paste glass ionomer type dental cement system, with both pastes being, preferably, of similar consistency. The first paste represents primarily a suspension of an inert filler in a water solution of polyacrylic acid, or its copolymers with other ethylenically unsaturated acids, having molecular weight of 25,000 to 100,000 and, optionally, various additives, such as filler suspending agents, coloring agents, agents influencing working/setting time (retardants or accelerators), Theological agents, pH modifiers, etc. The other paste represents primarily a particulate glass flux containing silicon and aluminum oxides, calcium fluoride and, optionally, other inorganic salts, including aluminum phosphate, and sodium, barium and aluminum fluorides, suspended in a liquid medium consisting primarily of a water solution of a hydrophilic acrylic monomer or polymer. In order to achieve a desirable consistency, organic or inorganic thickening agents may be added in suitable quantities.

Dental cement compositions

Adhesive coatings designed primarily for protecting, restoring, repairing, or modifying surfaces of, objects made of polymeric materials. Such coatings are particularly useful in application over worn, cracked, discolored, or otherwise defective objects made of polyacrylic, polystyrene, and polycarbonate resins. The adhesives of this invention are basically comprised of blends containing a substantial concentration of tetrahydrofurfuryl methacrylate and/or furfuryl methacrylate.

Adhesive coatings curable by light

A method of bonding polymeric articles to tooth structures employing a light curable primer, including etching the surface of said tooth, applying a primer to the polymeric article the primer including light curable acrylate or methacrylate monomers and a volatile solvent which softens or partially dissolves the polymeric material of the article, applying light curable adhesive to the article or tooth, and applying the article to the tooth and curing the primer and the adhesive by applying light.

Method of bonding article to teeth employing a light curable primer

There is provided a method for indirect bonding of chemically or light curable resin based restoratives especially acrylates and methacrylates, to the metal base of dental cast restorations. The invention is particularly useful in cases of in situ repairs of damaged or worn porcelain or polymeric veneers on cast restorations made of precious and non-precious metals. According to the invention, the exposed metal of the restoration is covered with a layer of primer consisting essentially of a copolymer of polymethacrylic or polyacrylic acid followed by the application of the polymerizable restorative material.

Method for repairing of veneered dental cast restoration

The present invention relates to a method of binding particles, in particular dental filling materials, comprising incorporating into the materials at least one compound selected from the group of diacrylic and dimethacrylic acid esters of the general formula ##STR1## wherein R.sup.1 is a divalent araliphatic, cycloaliphatic or aromatic group having 2 to 18 carbon atoms; R.sup.2 is hydrogen or methyl; R.sup.3 is a --CH.dbd.CH-- or --(CH.sub.2).sub.n -- wherein n is 2 to 4, a substituted, unsubstituted or hydrogenated benzene group, cyclohexane, or cis-norbornene group and R.sup.4 is H or ##STR2## wherein R.sup.5 is n-butyl, isobutyl, hexyl, substituted or unsubstituted phenyl or cyclohexyl. Dental restoratives and filling materials are also disclosed.

Growing community of inventors

West Covina, CA, United States of America

David V Butler