Biocare Medical, LLC

Other

David Tacha

Weimin Qi

John R Johnson

Thomas Marion Maxwell

Ravishankar Melkote

Hoa Thuong Nguyen

Evan Barker

Albert Coello

The present invention relates to compositions and detection systems of antibodies or fragments thereof, wherein at least two antibodies or fragments thereof binds specifically to squamous cell carcinoma (SCC) and/or adenocarcinoma (ADC). Methods for using the antibodies in diagnosis, prognosis, and assessing efficacy of treatment is further included as well as kits including such compositions and detection systems.

Antibody cocktail systems and methods for classification of histologic subtypes in lung cancer

The present invention is related to the anti-Uroplakin III antibodies, kits, cocktails, and use of anti-Uroplakin III antibodies for detection of cancer.

Systems and methods for anti-Uroplakin III antibodies

The present invention is related to the anti-SOX10 antibodies, kits, cocktails, and use of anti-SOX10 antibodies for detection of cancer.

Systems and methods for anti-SOX10 antibodies

Heat induced antigen retrieval systems for biological specimens may include a sealable heating pressure chamber, a programmable process controller, a nonpareil operating element, and perhaps even a substantially user-disencumbering autonomous processing component of a plurality of biological samples perhaps using various user selected protocols, and the like.

Methods and systems for immunohistochemistry heat retrieval of biological samples

The present invention is related to the anti-Uroplakin II antibodies, kits, cocktails, and use of anti-Uroplakin II antibodies for detection of cancer.

Anti-Uroplakin II antibodies systems and methods

Anti-SOX10 antibody systems and methods

The present invention is related to the anti-p40 antibodies, kits, cocktails, and use of anti-p40 antibodies for detection of cancer.

Anti-p40 antibodies systems and methods

Anti-uroplakin II antibodies systems and methods

The present invention is related to the anti-PAX8 antibodies, kits, cocktails, and use of anti-PAX8 antibodies for detection of cancer.

Systems and methods for anti-PAX8 antibodies

The present invention provide reagents and methods of using the reagents, for example, on automated staining devices, that facilitate detection of two or more antigens in a sample simply and efficiently.

Immunoassay reagents and methods of use thereof

A heating device for heating biological specimens is comprised of an electric pressure cooker with a pressure gauge, and a temperature sensor connected to a controller with a temperature display and a temperature alert. The controller is arranged to heat the specimen at a selectable temperature for a selectable time period. The quality control process is comprised of placing in the cooker a heat sensitive pH indicating retrieval solution, and a heat and pressure sensitive steam strip. When the set temperature has been reached, the actual temperature and pressure are recorded. When the cooker is opened after heating, the pH indicating solution is checked for color change that indicates a pH change, and the steam strip is checked for color change that indicates predetermined temperature and pressure levels have been reached.

Biological specimen heating device and quality control method for immunohistochemistry heat retrieval procedures

A microscope slide stainer includes a waste bin with an open top, and supporting notches arranged on the top edges of opposite sides. A slide supporting rack is supported in a horizontal position across the top of the bin in the supporting notches. The rack includes a pair of rails extending along a horizontal base. Brackets arranged on top of the rails define a plurality of spaced-apart slide holding positions. A hot plate is positioned between the rails and spaced above the horizontal base. A control box is attached to the hot plate for temperature control. Pins extending from opposite sides of the hot plate ride in direction-changing slots in the rails to enable the hot plate to be moved between a raised position engaged against the bottom of the slides, and a lowered position disengaged from the slides. Grooves are arranged on top surface of the hot plate to prevent the wet slides from sticking to it. A cover is removably positioned over the rack to define a heating and humidity chamber. The rack can be placed in a tilted position for rinsing the slides by inserting its ends in slanted slots extending downwardly from the supporting notches on the bin.

Growing community of inventors

San Ramon, CA, United States of America

David Tacha