Becton Dickinson and Company Limited

Duke University

David T Durack

Lawrence A Monahan

Artis R Lockhart

A self-injection device () for delivering a medicament includes a housing (), and a needle () connected to the housing (). A compressible reservoir () is connected to the housing () and is in fluid communication with a needle () such that compressing the reservoir () delivers medicament from the reservoir () to the needle () and moves the needle () from the first position to the second position. A platform () is disposed within the housing () about which the housing () is rotatable between a plurality of positions. Each of the positions corresponds to a different distance the needle () is moved to the second position during an injection to provide a variable injection depth. The needle () is withdrawn into the housing () after an injection without requiring manual manipulation by the user, thereby preventing needle sticks and other accidents.

Self-injection device

A method of determining (1) the activity of complement, (2) the bacteriolytic activity of serum, or (3) the titer of antibody in a sample which comprises: (a) incubating complement-sensitive microorganisms containing an assayable intracellular component with the sample, and (b) detecting the assayable component released into the sample by lysis of the microorganisms.

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Durham, NC, United States of America

David T Durack