Delta Biotechnology Limited

David St Coghlan

Richard A Johnson

Mark J Wilson

Steven James Burton

John Rodney Woodrow

Alan Victor Quirk

Stephen Berezenko

Patricia Carol Wood

Darrell Sleep

Andrew Robert Goodey

Hendrik Van Urk

A process is provided for the preparation of albumin which has extremely low levels of or is essentially free of colorants, metal ions, human proteins, fragments of albumin, polymers or aggregates of albumin, and viruses, and which is relatively non-glycated, relatively high in free thiol and with an intact C-terminus. The process comprises passing albumin (preferably expressed and secreted by transformed yeast) through two chromatography purifications, ultrafiltering the product, passing through two further chromatography steps and again ultrafiltering the product.

High purity albumin

A process for the preparation of albumin which has extremely low levels of or is essentially free of colorants, metal ions, human proteins, fragments of albumin, polymers or aggregates of albumin, and viruses, and which is relatively non-glycated, relatively high in free thiol and with an intact C-terminus. The process comprises passing albumin (preferably expressed and secreted by transformed yeast) through two chromatography purifications, ultrafiltering the product, passing through two further chromatography steps and again ultrafiltering the product.

High purity albumin and method of producing

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Beeston, United Kingdom

David St Coghlan