University of California

California Institute of Technology

David Sretavan

Hyuck Choo

Myung-Ki Kim

Chris Keller

Systems and methods of sensing intraocular pressure are described. An example miniaturized intraocular pressure (IOP) monitoring system is provided using a nanophotonics-based implantable IOP sensor with remote optical readout that can be adapted for both patient and research use. A handheld detector optically excites the pressure-sensitive nanophotonic structure of the IOP-sensing implant placed in the anterior chamber and detects the reflected light, whose optical signature changes as a function of IOP. Optical detection eliminates the need for large, complex LC structures and simplifies sensor design. The use of nanophotonic components improves the sensor's resolution and sensitivity, increases optical readout distance, and reduces its size by a factor of 10-30 over previous implants. Its small size and convenient optical readout allows frequent and accurate self-tracking of IOP by patients in home settings.

Systems and methods for sensing intraocular pressure

System and method for sensing intraocular pressure

Method and systems for nerve repair and for microfabrication. In specific embodiments, nerve repair is accomplished by repairing axons. In further embodiments, a modular, 3D system having very small dimentions is described. In further embodiments, a method ans system for performing surgery on axons is disclosed.

Nerve repair by selective surgical repair of axons

Methods and systems for constructing microfabricated devices including a microknife and methods and devices for a three-dimensional microstructure constructed from a plurality of separable planar components using one or more microfabrication techniques and optionally using one or more interlock structures.

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San Francisco, CA, United States of America

David Sretavan