Louisiana State University and Agricultural & Mechanical College

David Spivak

Cristina M Sabliov

Carlos Ernesto Astete

Tocopherol conjugates are disclosed that are useful as antioxidants or as pro-drug delivery vehicles. The conjugates are amphiphilic, and tend to localize at the interface between water domains and lipid domains. A prototype embodiment disclosed is an alpha tocopherol-linker-carnosine conjugate that has been designated VECAR.

Vitamin E conjugates, and their uses as antioxidants and prodrug delivery vehicles

A palladium catalyzed cross-coupling of aryldiazonium salts with organosilanes is disclosed. New reactions that are user friendly and environmentally friendly are now possible, including some reactions that could not be achieved using prior methods. The organosilanes that may be cross-coupled with aryldiazonium salts include, for example, Ar'&#x2014;Si(L), where Ar&#x2032;=aryl, and where L&#x2550;CH, OCH, F, Cl, R, or OR.

Growing community of inventors

Baton Rouge, LA, United States of America

David Spivak