Arthrex, Gmbh

David Shepard

Reinhold Schmieding

Thomas Dooney, Jr

Brandon Lee Roller

James L Cook

John Tokish

G Joshua Karnes

Robert Benedict

John Konicek

Brian Dorn

Anthony Orozco

Christopher Bare

James P Bradley

Robert Harrison

Gregory Joshua Karnes

James McWilliam

William T Pennington

Brian J Cole

Eric Giza

Matthew C Summitt

Tithi Dutta Roy

Lisa A Fortier

Reinhold Schmeiding

Adam Anz

Steve Jordan

Frank Grimaldi, Jr

Thomas Dooney

Brian Bartz

Steve Jordon

The present disclosure describes methods of treating an injury in a subject using placental tissue streamers, engineered tissue placental tissue hybrids, suture placental tissue hybrids, placental tissue patch hybrids, and tissue hybrids, and the use of these compositions to repair, treat, or support an injury or degenerative process in a subject.

Tissue use for repair of injury

The present disclosure describes methods of treating a ligament injury with ligament grafting.

Ligament reconstruction

A surgical method according to an exemplary aspect of the present disclosure includes, among other things, drying an osteochondral defect using a suction swab. The drying step includes suctioning moisture from the osteochondral defect through the suction swab or communicating a gas to the osteochondral defect through the suction swab.

Suction swab for surgical use

Techniques, mixtures, mixing and delivery kits, and improved delivery instruments for implantation of micronized allograft tissue over a microfractured defect. Allograft cartilage tissue is delivered over a cartilage defect that has been debrided and microfractured, without the need for a periosteal covering or separate type of patch sewn over the top. The allograft tissue may be any micronized cartilage particulates obtained by various methods, for example, cartilage delivered in its native form, dehydrated via lyophilization, 'freeze-dried,' dehydrated via desiccation, or dehydrated by any other method.

Implantation of micronized allograft tissue over a microfractured defect

A technique for knee replacement surgery that allow for the removal of an oval oblong-shaped allograft bone and cartilage plug from a donor distal femur. The technique uses instruments including (i) sizing guides to match the recipient's femoral size and curvature to that of a donor femur (the sizing guides also acting as a wide pin placement template for the donor distal femur); (ii) osteotomes that cut the curved and straight portions of the implant shape (these may be disposable or reusable); and (iii) templates that fit over the guide pins and have openings to allow the osteotomes to cut the donor femur plug to the correct size, shape and depth. The instruments allow for a non-circular shape to be extracted from a donor femur for use in a bone-saving osteoarthritis distal femur resurfacing procedure.

Method for forming non-circular cartilage grafts

Techniques and instruments for knee replacement surgery that allow for the removal of an oval oblong-shaped allograft bone and cartilage plug from a donor distal femur. The instruments include (i) sizing guides to match the recipient's femoral size and curvature to that of a donor femur (the sizing guides also acting as a wide pin placement template for the donor distal femur); (ii) osteotomes that cut the curved and straight portions of the implant shape (these may be disposable or reusable); and (iii) templates that fit over the guide pins and have openings to allow the osteotomes to cut the donor femur plug to the correct size, shape and depth. The instruments allow for a non-circular shape to be extracted from a donor femur for use in a bone-saving osteoarthritis distal femur resurfacing procedure.

Methods and instruments for forming non-circular cartilage grafts

A suture needle construct and method for extracapsular ligament reconstruction in mammals. The joint is first is first explored, and the damaged ligament and meniscus are debrided. The joint capsule is closed and a tunnel is created at the appropriate location in the proximal tibia for tibial fixation. Subsequent to the formation of the tibial tunnel, a suture having a substantially curved needle at one end and a substantially straight needle at the other end is brought in the proximity of the joint. The suture is passed around the lateral fabella using the substantially curved needle, then deep to the patellar ligament using the substantially straight needle, and through the tibial tunnel using the straight needle. The needles are cut off, and the sutures are tensioned over repair site.

Method and suture needle construct for cruciate ligament repair

Apparatus and methods for producing interleukin-1 receptor antagonist and/or other prophylatically or therapeutically effective protein. Blood is obtained from a patient with a conventional syringe and then introduced into dual luer lock centrifuge tube. The dual luer lock centrifuge tube is provided with beads that are coated with a silanized coating. The container is then incubated and centrifuged. Subsequent to the incubation and the centrifugation, the serum containing autologous therapeutically active protein, such as IL-1Ra, in the container is withdrawn through the luer lock of the container, and injected back into the patient.

Cytokine concentration system

An apparatus and method for stabilization of a cranial cruciate ligament deficient stifle in canines using a suture-button construct. The method includes the steps of drilling a femoral hole across a distal femur, passing a needle with a pull-through suture strand of a suture-button construct through the femoral hole, and applying a tensile force to the pull-through suture strand and a suture tape or strand of the construct such that a first button of the suture-button construct lies sideways for passage through the femoral hole, advancing the first button through the femoral hole by pulling the pull-through suture strand until the first button exits the femoral hole, drilling a tibial hole and passing the needle with the pull-through suture strand through the tibial hole, applying a tensile force to the pull-through suture strand and the suture tape or strand of the construct such that the first button lies sideways for passage through the tibial hole, flipping the first button to engage the first button against the medial tibial cortex and subsequently cutting and removing the pull-through suture strand, pulling free ends of the suture tape or strand to advance a second button of the suture-button construct and to seat the second button against the femur, and securing the second button against the femur.

Method and suture-button construct for stabilization of cranial cruciate ligament deficient stifle

A method and apparatus for repairing isolated chondral defects using allograft implants. Lesions in articular tissue are corrected by forming a recipient socket in the tissue. A donor graft of a size corresponding to the recipient socket is harvested from a partial tissue specimen obtained from allograft material. The donor graft is implanted into the recipient socket.

Osteochondral repair using plug fashioned from partial distal allograft femur or condyle

An osteochondral centrifugation system for providing an osteochondral centrifuged core from a graft such as femoral condyle, for example. The centrifugation system may be used either in the operating room or, alternatively, at a tissue banking facility at the time of processing. The osteochondral centrifuged core is formed by (i) removing an osteochondral core from a graft; (ii) placing the osteochondral core in a centrifugation system to remove blood, lipids, or other potentially antigenic or contaminating materials, and to obtain a centrifuged core; and (iii) optionally, subjecting the centrifuged core to a material that reduces the chance of disease transmission and aids in the healing of the recipient site to which the centrifuged core is to be transferred.

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Naples, FL, United States of America

David Shepard